It may be for how you approach epidemiologically speaking a mitigation strategy of such behavior, but for the potential of causing epidemic behaviors it is pretty clear. The question is on average to distinguish if the burden of one of the other is that different?
If it's not a homogenous state then the central premise is flawed - endemicity could result in much higher infection rates among vulnerable populations over time
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It also could be lower, what guarantees can you make about the state of the system over time if it is not based on the total energy of the system? On an epidemic state, energy is high, transitions are high probability. Cannot be worse.
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If restrictions reduce the overall number of infections substantially to the point where a vaccine is produced, it could be very substantially worse. This is the problem with purely theoretical models
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