So, >80% of you people would either be pretty skeptical of a paper like this or wouldn't trust it at all Yes, it is indeed a real paper https://twitter.com/GidMK/status/1302857005531459584 …pic.twitter.com/iWFg5cEIdS
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Agreed. Looks like a Russian MDD trial I saw once. NONE of the patients reported any AEs. Yup, read it and weep. (Patients with major depressive disorder feeling juuuust fine overall, over the course of an entire efficacy/safety trial?)pic.twitter.com/mE0UJQ8lqE
I once had a role in randomizing patients in a prostate cancer vaccine trial and we had a flow chart like this - of course the n was 6 and the followup was 16 weeks. The larger the n and the longer the follow up and the sicker the population the less likely you will see this.
If I had to guess I would say the odds of pulling this off with a study size greater than about a dozen is zero.
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