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GidMK's profile
Health Nerd
Health Nerd
Health Nerd
Verified account
@GidMK

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Health NerdVerified account

@GidMK

Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him

Sydney, New South Wales
theguardian.com/profile/gideon…
Joined November 2015

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    1. Health Nerd‏Verified account @GidMK 19 Aug 2020

      9/n Moreover, the risk of bias assessment in the systematic review is, as far as I can tell, incorrect. The authors of these studies do not report, for example, how the randomization procedure was generatedpic.twitter.com/B4C8gf8D3d

      1 reply 1 retweet 42 likes
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    2. Health Nerd‏Verified account @GidMK 19 Aug 2020

      10/n They also don't describe blinding of clinical staff, and actually from reading I'm fairly sure the doctors could tell which medication the patients were taking

      2 replies 0 retweets 42 likes
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    3. Health Nerd‏Verified account @GidMK 19 Aug 2020

      11/n Another issue for the SR/MA is that the data extraction from one of these studies is just wrong Here, honey has a mean reduction of 2.4 in cough frequency compared to 1.2 for 'usual care'pic.twitter.com/ucdT2kwMzO

      1 reply 0 retweets 33 likes
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    4. Health Nerd‏Verified account @GidMK 19 Aug 2020

      12/n Now, firstly, that's the reduction not for "honey" but for "honey + coffee", and it's being compared to a control of "coffee alone" which is definitely not what this analysis is looking atpic.twitter.com/tLFg7h58Dn

      1 reply 0 retweets 44 likes
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    5. Health Nerd‏Verified account @GidMK 19 Aug 2020

      13/n But further to this, the number given in the meta-analysis of -2.4 is wrong, as it should be 3.0-0.4 = -2.6 So it's wrong in two ways, both of them very bad for this analysis

      1 reply 0 retweets 28 likes
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    6. Health Nerd‏Verified account @GidMK 19 Aug 2020

      14/n I should also mention, both of these studies were rated as at low/moderate risk of bias in the systematic review. Have a look yourself and see if you think that this is reasonable: https://www.sid.ir/en/journal/ViewPaper.aspx?ID=196449 … https://www.nature.com/articles/pcrj201372#Sec9 …pic.twitter.com/UnJ3TNif3y

      1 reply 0 retweets 32 likes
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    7. Health Nerd‏Verified account @GidMK 19 Aug 2020

      15/n I haven't gone through every study yet, but every one that I have is similarly worrying. I can't actually find a study that I'm not worried about in this analysis

      1 reply 0 retweets 45 likes
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    8. Health Nerd‏Verified account @GidMK 19 Aug 2020

      16/n If I go through the studies, I really can't find any that I would rate as a "low" risk of bias. Most of them are "high", some of them are really worryingly bad

      1 reply 0 retweets 32 likes
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    9. Health Nerd‏Verified account @GidMK 19 Aug 2020

      17/n Given this, I'm not sure the conclusions of the review make much sense at all. How can you interpret studies of this quality as moderate/strong evidence???pic.twitter.com/mvlxiUAvJX

      3 replies 1 retweet 45 likes
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    10. Trent  💊 🆔‏ @trentyarwood 19 Aug 2020
      Replying to @GidMK

      prepared to ignore poor quality meta if it leads to fewer antibiotic prescriptions

      2 replies 0 retweets 2 likes
      Health Nerd‏Verified account @GidMK 19 Aug 2020
      Replying to @trentyarwood

      What if it leads to lots of people taking honey instead of getting treatment for their persistent coughs?

      7:38 PM - 19 Aug 2020
      0 replies 0 retweets 0 likes

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