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GidMK's profile
Health Nerd
Health Nerd
Health Nerd
Verified account
@GidMK

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Health NerdVerified account

@GidMK

Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him

Sydney, New South Wales
theguardian.com/profile/gideon…
Joined November 2015

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    1. Health Nerd‏Verified account @GidMK 13 Aug 2020

      The Mayo Clinic convalescent plasma for COVID-19 study is such a depressing waste of time it is frightening After treating THIRTY-FIVE THOUSAND patients, we still have no idea if the treatment workshttps://www.statnews.com/2020/08/13/large-study-suggests-convalescent-plasma-can-help-treat-covid-19-with-caveats …

      12 replies 49 retweets 137 likes
      Show this thread
    2. Health Nerd‏Verified account @GidMK 13 Aug 2020

      @matthewherper hits the nail on the head here - despite the impressive number of patients, the results are essentially uninterpretablepic.twitter.com/wB0MPHmKTD

      3 replies 2 retweets 19 likes
      Show this thread
    3. Health Nerd‏Verified account @GidMK 13 Aug 2020

      There are literally hundreds of reasons that some people might have gotten plasma early rather than late, in particular that they were less sick so they could tolerate the treatment This makes the study a bit worthless in terms of causal interpretation

      1 reply 1 retweet 12 likes
      Show this thread
    4. Health Nerd‏Verified account @GidMK 13 Aug 2020

      Thing is, the numbers are something of an indictment in and of themselves With 35,000 people to treat, it would be TRIVIAL to randomize 10% and do a proper trial

      2 replies 2 retweets 12 likes
      Show this thread
    5. Health Nerd‏Verified account @GidMK 13 Aug 2020

      This study could've paved the way for a successful treatment. Instead, we are now months into a pandemic, with billions spent on these patients, and still have no idea if what Mayo did was worthwhile or a waste of time

      1 reply 3 retweets 20 likes
      Show this thread
      Health Nerd‏Verified account @GidMK 13 Aug 2020

      Worse, it's entirely possible that the treatment is harmful, but without an appropriate control group we can only hope that it isn't Very, very depressing

      10:42 PM - 13 Aug 2020
      • 1 Retweet
      • 25 Likes
      • Enrique Espinosa Davide Maestri Hussain Gilani CWebb0412 Harry Hong Laura McCall #NoMassInfection Tanveer Batth Aslak Raanes Sueytonius
      3 replies 1 retweet 25 likes
        1. New conversation
        2. Health Nerd‏Verified account @GidMK 13 Aug 2020

          Also worth noting that for the main finding - i.e. people getting plasma early died less than those who got it late - THEY DIDN'T EVEN ADJUST FOR AGE AND SEX That's just...woeful. Maybe people who get plasma later are just older???

          1 reply 1 retweet 24 likes
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        3. Health Nerd‏Verified account @GidMK 13 Aug 2020

          I mean, it's an observational study where they're comparing two groups, getting headlines across the world, but they haven't adjusted that estimate for ANYTHING including things that might make a huge difference

          1 reply 0 retweets 14 likes
          Show this thread
        4. Health Nerd‏Verified account @GidMK 13 Aug 2020

          Have to say, the more I think about it the worse this study looks All these authors and no one thought to adjust for age? Or gender? Or one of the many biases that are likely to be present here?pic.twitter.com/z0UKMVKqTb

          4 replies 2 retweets 28 likes
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        5. End of conversation

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