16/n The obesity rates are referenced to the CIA world factbook Problem is, this data was last entered in 2016, and often is cited to sources up to a decade old So it's really very out of date!
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27/n You'd want to see case numbers by day, along with every intervention (i.e. social distancing, school closures etc) and the day they were implemented for every country on the list Then, number of HCQ doses given by day AT AN ABSOLUTE MINIMUM
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28/n Even if the authors make the suggested changes up until 25/n, they'd just end up with a meaningless correlation without measures like these, which are an enormous amount of work The thing about ecological studies is that the good ones take A LOT of time
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29/n Oh, another thing The authors keep maintaining on Twitter that this study was "random" because patients didn't choose what treatment they got, countries did This is absolute nonsense
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30/n Firstly, it is misdefining random If ANYONE chooses the treatment, then it's not random BY DEFINITION Random means no one chooses, it's that simple
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31/n But also - PATIENTS DID CHOOSE This is where we get back to the ecological fallacy - it is absurd to suggest that individuals within countries didn't choose to take HCQ. Even countries that authorised it had adopters and non-adopters
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32/n This protocol was BY NO POSSIBLE DEFINITION "random" Using the term is incorrect, and at best ignorant not just of the scientific terminology but also the colloquial meaning of the word
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End of conversation
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