I disagree that it's special. There a several drugs with low side effect profiles that have been tested for COVID-19. But really all of this is immaterial because if it doesn't work - which, as you agree, is unlikely - then it doesn't really matter anyway
I'm not sure I agree with that at all. A reduction in proportion of PCR-positive cases of less than 3.5% would be pretty small
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Sure, but at low rates of transmission. Also, the study was really quite large - >2,000 people - so presumably to find a smaller effect with low rates of transmission you'd need tens of thousands at a minimum
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