Before COVID, could you tell the difference between infection fatality rate and case fatality rate?
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I don't know that it is even now. Despite the huge attention paid to serosurveys and the effort to determine a 'true' IFR, I'm not sure it has told us anything important that we didn't already know
End of conversation
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At least in the U.S., to the best of my knowledge there are no routine serosurveys for influenza, and the best answer to "what is the IFR of flu" is "don't know". It's NOT 0.1 or 0.2. That is a zombie statistic that will not die.
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If the CFR for influenza is about 0.1%, what is its IFR? Because I’m seeing people now compare the COVID IFR to the influenza 0.1%, but they should be comparing it to an influenza IRF which I assume is significantly lower than 0.1% as well?
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So I wasn’t going crazy after all? I just thought everyone else understood the distinction.
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Much harder to work out number infected for flu (ie denominator for IFR), as serology can indicate prior infection. Best study for this probably UK Flu Watch.https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(14)70034-7/fulltext …
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I've been referencing this systematic reviewhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809029/ …
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