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GidMK's profile
Health Nerd
Health Nerd
Health Nerd
Verified account
@GidMK

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Health NerdVerified account

@GidMK

Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him

Sydney, New South Wales
theguardian.com/profile/gideon…
Joined November 2015

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    Health Nerd‏Verified account @GidMK 1 Jun 2020

    I don't know who needs to hear this today, but the placebo effect probably isn't real and mostly describes common statistical failings of scientific research

    2:33 PM - 1 Jun 2020
    • 37 Retweets
    • 137 Likes
    • Ander Sagarduy a misanthrope iPhone13 Pro Max #CCPliedMillionsDied Vivian Imbriotis Hank Rafal KiaKielo Leonardo Rodríguez Lagos Gustavo Nakaoka
    31 replies 37 retweets 137 likes
      1. New conversation
      2. Health Nerd‏Verified account @GidMK 1 Jun 2020

        To put it another way: Roses are red, Violets are green, The placebo effect is mostly just regression to the mean

        2 replies 13 retweets 108 likes
        Show this thread
      3. Health Nerd‏Verified account @GidMK 1 Jun 2020

        Lots of people asking, so here's the basic explanation. For subjective outcomes (i.e. pain) there's some evidence that placebos have a benefit. However, this is problematic because it could be due to reporting bias

        1 reply 2 retweets 17 likes
        Show this thread
      4. Health Nerd‏Verified account @GidMK 1 Jun 2020

        This means that people could be reporting that they think they've improved when, objectively, they haven't Which is exactly what we see when we look at objective outcomes

        2 replies 3 retweets 14 likes
        Show this thread
      5. Health Nerd‏Verified account @GidMK 1 Jun 2020

        So, for example, you might find that people with hypertension report feeling better after taking a placebo, but they don't actually have lower blood pressure

        1 reply 2 retweets 11 likes
        Show this thread
      6. Health Nerd‏Verified account @GidMK 1 Jun 2020

        Or people may report a reduction in pain, but they don't take fewer pain relief medications despite the placebo subjectively improving their response

        1 reply 2 retweets 12 likes
        Show this thread
      7. Health Nerd‏Verified account @GidMK 1 Jun 2020

        This is all summarized very well in a 2001 systematic review in NEJMhttps://www.nejm.org/doi/full/10.1056/NEJM200105243442106 …

        2 replies 4 retweets 34 likes
        Show this thread
      8. Health Nerd‏Verified account @GidMK 1 Jun 2020

        Many of the claimed benefits to the placebo effect (blue pills work TWICE as well as red!) are based on surprisingly terrible research from decades ago If you want to know more, I strongly recommend listening to @mikehall314 on Skeptics With A K, very comprehensive reviews

        4 replies 3 retweets 30 likes
        Show this thread
      9. End of conversation
      1. Viljami‏ @enjoyingthewind 1 Jun 2020
        Replying to @GidMK

        Omg, for real?

        0 replies 0 retweets 0 likes
        Thanks. Twitter will use this to make your timeline better. Undo
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      1. New conversation
      2. Gregory Herczeg‏ @GregHerczeg 1 Jun 2020
        Replying to @GidMK

        I prefer the half of studies that demonstrate the benefits of a placebo, they put my mind at ease.

        1 reply 0 retweets 3 likes
      3. Wael Hussein‏ @Teknofiliac 1 Jun 2020
        Replying to @GregHerczeg @GidMK

        Particularly the blue ones

        0 replies 0 retweets 0 likes
      4. End of conversation

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