Big #COVID19 news today
- hydroxychloroquine almost certainly not beneficial
- remdesivir likely beneficial but no silver bulletpic.twitter.com/WxqT1gazWm
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"Serious adverse events were reported for 114 of the 541 patients in the remdesivir group who underwent randomization (21.1%) and 141 of the 522 patients in the placebo group who underwent randomization (27.0%)." Is this unusual? Were symptoms misinterpreted as adverse effects?
In this context the adverse events are predefined then counted. The detailed breakdown gives you an idea of what is in there
Mechanistically the results make sense. Interrupting viral reproduction when someone is already in organ failure isn’t likely to do a lot.
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