Donald Trump taking hydroxychloroquine to ward off coronavirus is an AMAZING lesson in how awful people are at evaluating research (because it doesn't work)pic.twitter.com/SgqpVoOpOJ
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Yes, but still an independent hypothesis needing RCT, especially if dependent upon different mechanism for effectiveness... I just think it’s good practice in this rhetorically fraught situation to be clear what we mean when we say “it doesn’t work” https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30296-6/fulltext …
Rhetorically fraught as in there is a risk to the public health and scientific messaging re: COVID in the case where HCQ is shown to be both safe and effective for prophylaxis despite messaging that it is neither safe nor effective as later-stage treatment... Nuance is needed
With numbers of new cases falling in a lot of countries, do you think we're past the point where we can realistically arrange an appropriately sized prophylaxis RCT?
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