I decided to delve into the "Vitamin D can cure COVID-19" articles to see what the fuss is about and this is WILD Blog forthcoming, but holy shit this is the worst argument I've seen in a very long timepic.twitter.com/UUIZzPtUTN
Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him
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I decided to delve into the "Vitamin D can cure COVID-19" articles to see what the fuss is about and this is WILD Blog forthcoming, but holy shit this is the worst argument I've seen in a very long timepic.twitter.com/UUIZzPtUTN
The basic story - two studies correlated PAST measurements of Vitamin D levels with CURRENT COVID-19 deaths and concluded that it might be implicated This is such staggering nonsense I don't know where to start...
Did people who died from the disease actually HAVE low Vit D levels? Was this the case BEFORE the disease onset? What confounding factors might be at play? We have NO IDEA!!! Epidemiological nonsense
Here is a study that measured 25(OH)D in hospital patients before, and during admission - and after: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3571484 … Would be intererested in your thoughts, and the other clinical studies that are pretty easy to track down.
Well, their statistical analysis is wrong - they are predicting Vitamin D levels using clinical outcomes, which is entirely the wrong way around. With no control for age at all, hard to know what any of it means unfortunately
Maybe I’m reading the paper wrong then (and Dr John Campbell too) https://www.youtube.com/watch?v=GCSXNGc7pfs&t=873s … The vitamin D levels are measured not predicted. They adjust for age and comorbidity. (and of course severe defficiency would contribute to some comorbidities)pic.twitter.com/AbUvlpyA6X
That's not the paper you linked to, but it has its own issues as well. Not a very good analysis, and the patient selection process was a worry - this is actually a case-control study where they picked people based on whether they died from COVID-19
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