I decided to delve into the "Vitamin D can cure COVID-19" articles to see what the fuss is about and this is WILD Blog forthcoming, but holy shit this is the worst argument I've seen in a very long timepic.twitter.com/UUIZzPtUTN
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Did people who died from the disease actually HAVE low Vit D levels? Was this the case BEFORE the disease onset? What confounding factors might be at play? We have NO IDEA!!! Epidemiological nonsense
And yet, hundreds of articles and I've already been told by several people that they're taking supplemental Vit D because of it
There's some evidence from studies of Vit D being useful for OTHER respiratory infection, but many of these studies looked at people with asthma and it's hard to know if this would transfer to infection with COVID-19
It's also worth noting that there doesn't seem to be any good evidence of Vitamin D protecting against DEATH from infection, which is really what we care about
Blog is now up, there were even more studies out there any some of them were even worse somehowhttps://medium.com/the-method/should-you-take-a-vitamin-d-supplement-for-covid-19-63d922f24953 …
That’s “here’s something someone should have a look at”.
The link to COVID-19 specifically is only a correlation at the moment but past studies have shown a casual link between vitamin d supplementation and greatly reduced risk (up to 70% in those deficient) of respiratory tract infections in controlled trialshttps://www.bmj.com/content/356/bmj.i6583 …
I actually am quite unsure about that SR/MA. They found what appears to be quite significant publication bias if you look in the supplementary materials, but made no correction for it at all. Better-quality studies seemed to find no benefitpic.twitter.com/bOGbFIvkiT
You're dangerously close to finding my previously mentioned worst-study-ever. I don't think you've found it yet, but you're getting there.
Is it the Indonesian case-control study of Vit D that's apparently definitive evidence despite a) not calling itself a case-control b) not defining ANYTHING about how participants were selected and c) being pretty dicey ethically?
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