There’s been controversy over the changed primary endpoint in the NIAID remdesivir study.
NIAID tells me the original endpoint would also have been significant.
Featuring @walidgellad.https://www.statnews.com/2020/05/05/were-researchers-wrong-to-move-the-goalposts-on-remdesivir-in-the-end-it-may-not-have-mattered/ …
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Replying to @matthewherper @walidgellad
Thanks for digging into this:pic.twitter.com/GtOmCYcJK3
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...because I really don't think a lot of the folks that commented early on the endpoint change appreciated this process; when they saw that the endpoint was changed on http://clinicaltrials.gov on April 2, they assumed that was the day the decision was made.
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Who'd have ever thought that running RCT's in the midst of a pandemic could be so complicated?
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Really exasperating to see so many assume that "April 2 change on http://clinicaltrials.gov " meant that the decision was made that day, and to see how many assume that it must have been made based on knowledge of the data, rather than a blinded decision.
3 replies 0 retweets 5 likes
I tried not to make assumptions, but the problem was all we got was 4 lines in a press release and virtually no other information about the study. Not great communication, that
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