DRUGS HYPED EARLY FOR TREATMENT OF #COVID19:
HCQ/CQ
Remdesivir
Ritonavir/lopinavir
DRUGS THAT HAVE HAD LARGE, WELL-CONDUCTED RCTs COME BACK NEGATIVE FOR BENEFIT IN TREATING #COVID19:
HCQ/CQ
Remdesivir
Ritonavir/lopinavir
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This does not mean that none of these drugs 'work', but so far the best evidence seems to suggest no benefit for any of them And yet, some people are still hyping them
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Also, both "large" and "well-conducted" in the initial tweet are to an extent relative All of the trials were >150 participants, but all had some risk of bias. Not a definitive pronouncement by any means, but still some fairly compelling results
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