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GidMK's profile
Health Nerd
Health Nerd
Health Nerd
Verified account
@GidMK

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Health NerdVerified account

@GidMK

Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him

Sydney, New South Wales
theguardian.com/profile/gideon…
Joined November 2015

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    1. Health Nerd‏Verified account @GidMK 13 Apr 2020

      Health Nerd Retweeted Brian Dunning

      Wow❗️Reasonably large RCT of high-dose chloroquine vs low-dose chloroquine (all patients received azithro) At 6 days, high-dose CQ group had 17% mortality compared to 10% in the low-dose group No benefit to high-dose CQ on lung parameters, trial stopped earlyhttps://twitter.com/BrianDunning/status/1249825311354650629 …

      Health Nerd added,

      Brian DunningVerified account @BrianDunning
      A small (n = 440) Brazillian trial of chlorquine (not hydroxychloroquine) alongside azithromycin has been halted after 20 days because the drug had no benefit for #COVID19 patients and was killing people. https://clinicaltrials.gov/ct2/show/NCT04323527 … Do. Not. Recommend. Unproven. Therapies.
      6 replies 90 retweets 191 likes
      Show this thread
    2. CookieDoughEater‏ @shopwithoutkids 13 Apr 2020
      Replying to @GidMK @DrJenGunter

      So they only stopped the high dose arm per preprint? Also, only compared with hx controls for no tx , no placebo arm. I agree that we shouldn’t jump on HCQ bandwagon, but would like more definitive data. But appears that all this showed was a trend towards >tox in high dose?

      1 reply 0 retweets 1 like
    3. Health Nerd‏Verified account @GidMK 13 Apr 2020
      Replying to @shopwithoutkids @DrJenGunter

      Pretty much. According to preprint, CQ/HCQ was mandated as a treatment at a federal level in Brazil, so both arms had to receive it. Higher dose appeared to be dying more so trial halted early

      0 replies 0 retweets 4 likes
    4. This Tweet is unavailable.
      Health Nerd‏Verified account @GidMK 14 Apr 2020
      Replying to @Katvonkit @shopwithoutkids @DrJenGunter

      Interesting. Maybe the language was confused? It implied that the patients were required to have the drug

      4:38 AM - 14 Apr 2020
      0 replies 0 retweets 0 likes

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