There were also a large number of reported side-effects, although given the lack of a control group and how sick these people were it's very hard to know if they had anything to do with remdesivirpic.twitter.com/9YS5cmlhxm
Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him
You can add location information to your Tweets, such as your city or precise location, from the web and via third-party applications. You always have the option to delete your Tweet location history. Learn more
Add this Tweet to your website by copying the code below. Learn more
Add this video to your website by copying the code below. Learn more
By embedding Twitter content in your website or app, you are agreeing to the Twitter Developer Agreement and Developer Policy.
| Country | Code | For customers of |
|---|---|---|
| United States | 40404 | (any) |
| Canada | 21212 | (any) |
| United Kingdom | 86444 | Vodafone, Orange, 3, O2 |
| Brazil | 40404 | Nextel, TIM |
| Haiti | 40404 | Digicel, Voila |
| Ireland | 51210 | Vodafone, O2 |
| India | 53000 | Bharti Airtel, Videocon, Reliance |
| Indonesia | 89887 | AXIS, 3, Telkomsel, Indosat, XL Axiata |
| Italy | 4880804 | Wind |
| 3424486444 | Vodafone | |
| » See SMS short codes for other countries | ||
This timeline is where you’ll spend most of your time, getting instant updates about what matters to you.
Hover over the profile pic and click the Following button to unfollow any account.
When you see a Tweet you love, tap the heart — it lets the person who wrote it know you shared the love.
The fastest way to share someone else’s Tweet with your followers is with a Retweet. Tap the icon to send it instantly.
Add your thoughts about any Tweet with a Reply. Find a topic you’re passionate about, and jump right in.
Get instant insight into what people are talking about now.
Follow more accounts to get instant updates about topics you care about.
See the latest conversations about any topic instantly.
Catch up instantly on the best stories happening as they unfold.
There were also a large number of reported side-effects, although given the lack of a control group and how sick these people were it's very hard to know if they had anything to do with remdesivirpic.twitter.com/9YS5cmlhxm
As a fun statistical point, the confidence intervals for some of these regression analyses were, uh, pretty wide Older patients had between 35% and 9417% increase risk of death!pic.twitter.com/HMsGPPYXfs
So what does this all mean? Well, the authors talk about it in their discussion Apparently, the mortality rate was lower than expected, which is "noteworthy"pic.twitter.com/VCSblvjbs5
Health Nerd Retweeted Health Nerd
Now, I'd argue that this is...problematic It is extremely difficult to compare patients across trials, and absolutely NOT best practice We also saw a high dropout rate in the trial, with 20% of patients not receiving the complete treatment!https://twitter.com/GidMK/status/1249547200834580485?s=20 …
Health Nerd added,
We also have very few patients in this trial, and no control group Also, the patients were selected by their doctors - perhaps picking the patients that they thought had a fighting chance? We can't really say whether the death rate was low or high from the data we have!
To the author's credit, the final paragraph acknowledges most of this!pic.twitter.com/0TdO2drS1C
Let's sum up:
very small retrospective trial
no control group
written by pharma funder
high dropout
short timeframe
missing data
poorly written/edited
somewhat odd stats
highly selected patient cohort
no causal conclusions!
Basically, it was a very small study with HUGE caveats that showed an interesting possibility Hard to say anything more than that without a proper trial of some kind
Some might argue that this should not have been published as a research trial, given the many caveats and huge conflicts of interest this study seems to contain
I guess that's a question for @NEJM, who appear to have garnered millions of reads on the article in the last few days
Excellent, & balanced, critique - thanks...! ...if published as a 'Preliminary report' rather than 'Original article' it might have been less disingenuous?
Twitter may be over capacity or experiencing a momentary hiccup. Try again or visit Twitter Status for more information.