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GidMK's profile
Health Nerd
Health Nerd
Health Nerd
Verified account
@GidMK

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Health NerdVerified account

@GidMK

Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him

Sydney, New South Wales
theguardian.com/profile/gideon…
Joined November 2015

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    1. Elaine Kenny‏ @elaneyk1 20 Mar 2020

      @SequencingCom what exactly are you using to base this report on? Anyone have any opinions on this?? I'm going for heap of 💩 @US_FDA @codushlaine @GidMK @DrRobertOConnor @ricanney @TheSciBabepic.twitter.com/eGzvrD3Vtp

      2 replies 6 retweets 8 likes
    2. Sequencing‏ @SequencingCom 20 Mar 2020
      Replying to @elaneyk1 @codushlaine and

      The DNA analysis is based on 20+ peer reviewed genetic association studies that identified specific genetic variants as either impact susceptibility to Coronavirus or risk of Coronavirus infection progressing to severe illness. The analysis also includes non-genetic factors.

      2 replies 0 retweets 0 likes
    3. Colm O'Dushlaine‏ @codushlaine 20 Mar 2020
      Replying to @SequencingCom @elaneyk1 and

      Sounds interesting, can you send on the references?

      3 replies 0 retweets 3 likes
    4. Sequencing‏ @SequencingCom 20 Mar 2020
      Replying to @codushlaine @elaneyk1 and

      Here’s an example of the results. The genetic variants are listed near the bottom of the report in the DNA Data table and include Pubmed link outs to the relevant studies:https://sequencing.com/dna-apps/coronavirus-dna-health-report/example/child-increased-genetic-risk …

      1 reply 0 retweets 0 likes
    5. Health Nerd‏Verified account @GidMK 20 Mar 2020
      Replying to @SequencingCom @codushlaine and

      So, looking at the references this all basically vague inference using 1 or 2 SARS studies. You should at the very least be clear in the report that this is incredibly uncertain and may not be a reflection of true risk in any way

      2 replies 0 retweets 4 likes
    6. Elaine Kenny‏ @elaneyk1 20 Mar 2020
      Replying to @GidMK @SequencingCom and

      Also seems to rely heavily on variants in ACE2 gene and studies from SARS/MERS infection. A bit of a leap considering this part in one of your listed references. "several key residues responsible for the binding.. were variable in 2019-nCoV". Dubious and misleading.pic.twitter.com/sQ5sQStrfQ

      2 replies 0 retweets 3 likes
      Health Nerd‏Verified account @GidMK 20 Mar 2020
      Replying to @elaneyk1 @SequencingCom and

      Indeed. Things like this are why I think direct-to-consumer genetic testing is often a bit of a scam

      4:30 PM - 20 Mar 2020
      • 2 Likes
      • Dr Robert O'Connor Elaine Kenny
      1 reply 0 retweets 2 likes
        1. New conversation
        2. Elaine Kenny‏ @elaneyk1 20 Mar 2020
          Replying to @GidMK @SequencingCom and

          The studies also indicate variable ACE2 gene expression in lungs associated with smoking, environmental risk not genetic...

          1 reply 0 retweets 2 likes
        3. Sequencing‏ @SequencingCom 20 Mar 2020
          Replying to @elaneyk1 @GidMK and

          There are several genes from other studies that are also included in the phenotype analysis. Only a single ACE2 variant is used in analysis as it is nonsense variant that destroys CoV-2 binding site.https://sequencing.com/dna-apps/coronavirus-dna-health-report/example/adult1-multifactorial-risks …

          0 replies 0 retweets 0 likes
        4. End of conversation

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