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GidMK's profile
Health Nerd
Health Nerd
Health Nerd
Verified account
@GidMK

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Health NerdVerified account

@GidMK

Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him

Sydney, New South Wales
theguardian.com/profile/gideon…
Joined November 2015

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    1. Dave Feldman‏ @DaveKeto 20 Jan 2020

      The first paragraph under “Increase Our Cholesterol” is worth reading multiple times... https://twitter.com/SaraTirner/status/1219392923260858376 …pic.twitter.com/G4mHdIYaWi

      21 replies 30 retweets 154 likes
    2. George Henderson‏ @puddleg 20 Jan 2020
      Replying to @DaveKeto

      I'm guessing this means that high cholesterol produced in response to a protective factor is the only type of high cholesterol you want. I'm down with that.

      2 replies 1 retweet 10 likes
    3. Health Nerd‏Verified account @GidMK 20 Jan 2020
      Replying to @puddleg @DaveKeto

      Potentially. Another potential explanation is survivorship bias (i.e. the only people who survive with increasing cholesterol until 85 are the healthier ones)

      3 replies 1 retweet 11 likes
    4. Dr. Spencer Nadolsky‏Verified account @DrNadolsky 20 Jan 2020
      Replying to @GidMK @puddleg @DaveKeto

      Yes this is the key

      1 reply 0 retweets 2 likes
    5. George Henderson‏ @puddleg 21 Jan 2020
      Replying to @DrNadolsky @GidMK @DaveKeto

      Survivorship bias is indeed the key, but what provides survivorship? Can it be in part attributed to healthy factors that can raise LDL by fat oxidation and are not associated with increased mortality or disease, or not likely to be? Dairy fat, fasting, coffee, keto, HI exercise?

      1 reply 2 retweets 1 like
    6. George Henderson‏ @puddleg 21 Jan 2020
      Replying to @puddleg @DrNadolsky and

      For example, the earliest incidence of LDL-related survivorship bias, at age 50, is occurring in a population with a high dairy fat intake. Most Danes would die or receive end-of-life diagnoses after the age of 50, wouldn't they?https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750440/ …

      2 replies 1 retweet 1 like
      Health Nerd‏Verified account @GidMK 21 Jan 2020
      Replying to @puddleg @DrNadolsky @DaveKeto

      That's unlikely to be survivorship bias (although not on age 50 people as you say, the youngest age included was 50+). However, I'd note that they didn't control for anything other than sex in their analysis, which makes the results very hard to interpret

      12:53 PM - 21 Jan 2020
      1 reply 0 retweets 0 likes
        1. Hap MD‏ @MDVilntfluid 22 Jan 2020
          Replying to @GidMK @puddleg and

          Hmmm. You should be so skeptical of lower cholesterol. Danes and French have the lowest IHD rates in the world.

          0 replies 0 retweets 0 likes
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