I find that #medicalstatistics (e.g. likelihood ratios) are, for me, akin to the internal combustion engine. I get that when press the pedal I speed up (LR>10), I release the pedal I slow down (LR< 0.1). But what happens inbetween to get that effect..? #BEEM @GidMK 
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I find all this strangely reassuring. I (try) to teach the Residents and Students a session on Pos and Neg predictive values and I freely admit I have to copy the 4x4 table every time and I also admit it makes my head hurt trying to force my brain to do the maths :)
End of conversation
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