The first paragraph under “Increase Our Cholesterol” is worth reading multiple times... https://twitter.com/SaraTirner/status/1219392923260858376 …pic.twitter.com/G4mHdIYaWi
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The fact that increasing cholesterol from midlife to age 75-84 had an entirely reversed association supports this, unless we're positing that 85+ have an entirely different reaction to cholesterol than other ages
That's consistent with the healthy factors causing the high cholesterol, as opposed to the unhealthy ones. For example, cholesterol rise is a known effect of fasting in the healthy, though whether this affects concentrations long-term is still unknown.
Mmmm, but it might not be about the cholesterol per se. Could be that mostly very fit people can survive past 85 with high cholesterol, for example
Yes this is the key
Survivorship bias is indeed the key, but what provides survivorship? Can it be in part attributed to healthy factors that can raise LDL by fat oxidation and are not associated with increased mortality or disease, or not likely to be? Dairy fat, fasting, coffee, keto, HI exercise?
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