Consider a prespecified secondary RCT endpoint that is missing 50% of the time. Is it okay to not report it *at all*?
If there's a sufficiently good explanation, sure. Say if you originally had access to a specific scan but it was then lost halfway through the trial, might bias the results and make them useless anyway
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If it is an RCT, why would that make it biased?
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Time-varying or crossover RCTs would have an issue. Might not be a problem in your standard 2-group design, depends on the situation
End of conversation
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