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GidMK's profile
Health Nerd
Health Nerd
Health Nerd
Verified account
@GidMK

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Health NerdVerified account

@GidMK

Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him

Sydney, New South Wales
theguardian.com/profile/gideon…
Joined November 2015

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    1. Health Nerd‏Verified account @GidMK 12 Nov 2019

      Now, the researchers used a counterbalanced design, which is a method of trying to account for this issue The problem here is that the study doesn't seem to have been randomized, which means that it's likely that bias crept into the results!pic.twitter.com/mXcw1pEngE

      1 reply 0 retweets 3 likes
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    2. Health Nerd‏Verified account @GidMK 12 Nov 2019

      That brings us to the next area of concern They excluded a quite a few participantspic.twitter.com/ILzsvHkjE5

      1 reply 0 retweets 2 likes
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    3. Health Nerd‏Verified account @GidMK 12 Nov 2019

      In total, out of the 91 children who started the trial, 8 dropped out That's actually pretty good, only 9%!

      1 reply 0 retweets 0 likes
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    4. Health Nerd‏Verified account @GidMK 12 Nov 2019

      But then, a further 7 were excluded because of 'poor hydration compliance' What does this mean? Essentially, the researchers thought they were drinking more/less water than their experimental conditionpic.twitter.com/PJXeqv0IG5

      1 reply 0 retweets 1 like
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    5. Health Nerd‏Verified account @GidMK 12 Nov 2019

      Now, this makes the study what's known as a per-protocol analysis Without going into the details, per-protocol analyses are KNOWN for giving spurious/misleading resultspic.twitter.com/o2G7Yissgq

      1 reply 0 retweets 4 likes
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    6. Health Nerd‏Verified account @GidMK 12 Nov 2019

      But there's more - after excluding participants entirely, the study excluded between 5 and 21 children from each analysis in the study That's up to 28% of the remaining sample (!)pic.twitter.com/j0KfldJaV2

      1 reply 0 retweets 3 likes
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    7. Health Nerd‏Verified account @GidMK 12 Nov 2019

      This was due to "poor cognitive data" What does that mean? Well, according to the study, it means that these kids had results that were considered 'outliers' or 'poor performance'pic.twitter.com/70Z3ZHH8rl

      1 reply 0 retweets 2 likes
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    8. Health Nerd‏Verified account @GidMK 12 Nov 2019

      Astute readers will note that this means that apparently 8/64 (13%!) of the children had results more than 3 standard deviations from the mean in the go/no-go task That seems...unlikely

      2 replies 0 retweets 3 likes
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    9. Health Nerd‏Verified account @GidMK 12 Nov 2019

      To give you an idea of how unlikely, I ran the mean/standard deviations through SPRITE (thanks @sTeamTraen @jamesheathers) for 100 repetitions, and didn't get a single distribution with more than 3% of results >3 SDs from the mean So...maybe possible? VERY weird

      2 replies 0 retweets 5 likes
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    10. Nick Brown‏ @sTeamTraen 13 Nov 2019
      Replying to @GidMK @jamesheathers

      Well, we don't know the mean and SD before the 19 participants were removed, but I agree that 8/73=11% of 3-SD outliers is a lot, and SPRITE is going to struggle to find solutions (e.g., with 8 "fixed" values of 901ms, in the first go/no-go line with M=600.6 and SEM=11.7->SD=100)

      1 reply 0 retweets 1 like
      Health Nerd‏Verified account @GidMK 13 Nov 2019
      Replying to @sTeamTraen @jamesheathers

      It seems very odd that they had so many outliers to me, surely at that point they aren't really outliers any more!

      12:06 PM - 13 Nov 2019
      1 reply 0 retweets 0 likes
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        2. Nick Brown‏ @sTeamTraen 13 Nov 2019
          Replying to @GidMK @jamesheathers

          Once you start selecting on the dependent variable, unless it's flagrantly bad, you are going to be in trouble. A number of their include/exclude decisions look very arbitrary to me.

          1 reply 0 retweets 1 like
        3. Health Nerd‏Verified account @GidMK 13 Nov 2019
          Replying to @sTeamTraen @jamesheathers

          That's definitely true. Cannot see why you'd exclude children with lower than 40% accuracy, seems like an entirely arbitrary decision 🤔

          1 reply 0 retweets 1 like
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