I get that it's easy to start with Edward Jenner when you want to talk history of vaccines, but smallpox inoculation (maybe not with cowpox but likely with a weakened or related version of the virus) predated him in Asia and the middle east.
I think inoculation implies a weakened form of the disease? I remember hearing on a podcast recently that variolation had a death rate of 10% because it basically just gave you a slightly less bad version of smallpox
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Ok, looked it up and I'm confusing terms. Inoculation is just the blanket term, variolation and vaccination are both types of inoculation
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I don't know if we know exactly what was in ancient eg Chinese inoculation material, but I recall reading that it was considered important to get the good stuff, from a responsible practitioner, because then it would make you less sick.
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