This is ~amazing~
Small RCT finds TOMATOES (lycopene) might improve SPERM (Altmetric 1454!)
Except, all results based on within-group pre/post comparisons, no controlling for multiplicity #statstwitter 


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Blog now up on thishttps://medium.com/@gidmk/tomatoes-wont-boost-your-sperm-989892658a13 …
I wish I had a witty line here. But all I can muster is resigned inner rage at the “within group pre-post comparison used to draw conclusions about treatment effect”
the means and SDs don't look like they'd play nice with a normal distribution either. for most of their measures -2*SD is less than zero.pic.twitter.com/AKc8ECscTj
I'll have to avoid puns here and be an adult, or this will quickly descend into ... no, I'm not doing it. So, here's the clinical trial reg. Primary outcome: Motile sperm concentration http://www.isrctn.com/ISRCTN33248724
Week 6 is in the registration, and mentioned in the paper, but the data is not reported. What happened to the midpoint variables?
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