Wow this study and the reporting is a massive trainwreck from start to finish NAPS CAN'T SAVE YOUR LIFE UGHpic.twitter.com/PAFWdJLDvF
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On top of this, there was ENORMOUS potential for residual confounding in this study For one thing, even the controls for confounding were based on some pretty simple variables (probably due to the sample itself)pic.twitter.com/gHPw2E6zZM
If nothing else, the fact that there were no controls for alcohol and drug use, which might impact both napping and CVD risk, makes the results quite challenging to interpretpic.twitter.com/1UekGHmQ2C
The authors acknowledged most of this in their limitations, because it's all fairly basic epidemiological stuff and they're clever scientistspic.twitter.com/IhZ0CJvxTR
But when you get to the press release, somehow much of the message that this potentially might not have anything to do with naps at all is lostpic.twitter.com/UtJ7RPNzyG
And then the headlines - especially the totally ridiculous "a nap can save your life" - are wildly off base
TL:DR - Swiss people who nap a little might be slightly healthier than those who don't nap at all - Might be more to do with age and OSA than naps themselves - No good reason to believe that naps are healthy
Also, forgot to mention, the relative risk decrease was large (50%!) but the absolute risk decrease for napping was more like 3% which is a bit less impressive
But small sample sizes tend to exaggerate effect sizes, not attenuate them
Oh the point estimate was still similar but the confidence interval grew quite a bit. The issue I have is that OSA is known to cause both napping and cardiovascular disease, so I cannot see how any analysis that doesn't adjust for it makes sense
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