This is not true. Stroke is at p=0.05 and ischemic at p<0.008. All other outcomes were individually significant except fatal MI. Nonfatal MI was 0.002. And that's with an incredibly modest change in LDL!!!pic.twitter.com/ZYEKGOvf90
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The references for "fatigue" (38,39) are a perspective piece and a conference abstract that was never written up as a paper as far as I can tell. The conference abstract, funnily enough, didn't show a "statistically significant" reduction from statinspic.twitter.com/FX4WM2OoSp
The reference for "exertional fatigue" is another publication from the same study as the previous conference abstract, which found a statistically (although arguable clinically) significant drop in energy of ~2% associated with statin usepic.twitter.com/RxBPUacHRn
The finding of a reversible change in personality shouldn't be minimized. This is the kind of finding that docs should be aware of. Low cholesterol has been associated with increased aggression.pic.twitter.com/UOL8g09qNv
I'd argue that it's pretty hard to make any definitive statements from a case series of 6 patients, and it certainly doesn't support the statement of "statistically significant" results as no statistical comparisons were made
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