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GidMK's profile
Health Nerd
Health Nerd
Health Nerd
Verified account
@GidMK

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Health NerdVerified account

@GidMK

Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him

Sydney, New South Wales
theguardian.com/profile/gideon…
Joined November 2015

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    1. Health Nerd‏Verified account @GidMK 11 Jul 2019

      The press release is here, and unsurprisingly I am not a fanhttps://www.sciencedaily.com/releases/2019/07/190710121607.htm …

      1 reply 0 retweets 14 likes
      Show this thread
    2. Health Nerd‏Verified account @GidMK 11 Jul 2019

      The study is pretty simple - the researchers took a very large database of children (1.3 million) and identified every cancer diagnosis in that group 1.3 million children, about 2,000 cases of cancer (childhood cancers are rare)

      1 reply 1 retweet 13 likes
      Show this thread
    3. Health Nerd‏Verified account @GidMK 11 Jul 2019

      They then compared the kids based on the characteristics of their mothers, in particular BMI, to see if that affected their risk of cancerpic.twitter.com/tiQQ5Wn9qz

      1 reply 1 retweet 8 likes
      Show this thread
    4. Health Nerd‏Verified account @GidMK 11 Jul 2019

      They found that there was a very weak relationship between maternal BMI and the risk of childhood cancer (p=0.01), although this risk didn't become statistically significant until mothers were above 40Kg/m^2 BMI

      1 reply 2 retweets 15 likes
      Show this thread
    5. Health Nerd‏Verified account @GidMK 11 Jul 2019

      They also found, in a piece of mind-blowing absurdity, that childhood leukemia was NOT statistically significantly related to maternal BMI (p-value highlighted)pic.twitter.com/r1r8sFEd5a

      3 replies 1 retweet 15 likes
      Show this thread
    6. Health Nerd‏Verified account @GidMK 11 Jul 2019

      I mean, we could take a non-frequentist approach and say that based on priors as well as the CI it's reasonable to make a connection there, but even so it's an amazing thing to omit from every report of the study

      1 reply 0 retweets 9 likes
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    7. Health Nerd‏Verified account @GidMK 11 Jul 2019

      It's also worth remembering that childhood cancer is VERY RARE The overall rate in this sample was 2,329 in 1,812,131 children The crude absolute risk increase was about 0.002% THAT'S TINYpic.twitter.com/KZsiqmGE2J

      1 reply 3 retweets 27 likes
      Show this thread
    8. Health Nerd‏Verified account @GidMK 11 Jul 2019

      Childhood cancers are awful, and very hard to prevent, but this still represents a truly miniscule risk increase and only for a small group of women

      1 reply 0 retweets 16 likes
      Show this thread
    9. Health Nerd‏Verified account @GidMK 11 Jul 2019

      Also, the headlines talking about OBESITY are wrong There was NO risk increase for women over 30 Kg/m^2 - medical obesity. The risk was only seen in women >40 Kg/m^2, which is quite a bit heavier

      1 reply 1 retweet 26 likes
      Show this thread
    10. Health Nerd‏Verified account @GidMK 11 Jul 2019

      There was also no control in the model for most confounding (they only controlled for age and race), which leaves the door wide open for alternate explanations

      2 replies 1 retweet 18 likes
      Show this thread
      Health Nerd‏Verified account @GidMK 11 Jul 2019

      Maybe more obese women are less wealthy, and therefore their kids are exposed to more carcinogens Maybe it's a whole host of complex social factors and we just aren't sure what's going onpic.twitter.com/MscqXrIeAb

      8:56 PM - 11 Jul 2019
      • 2 Retweets
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      2 replies 2 retweets 49 likes
        1. New conversation
        2. Health Nerd‏Verified account @GidMK 11 Jul 2019

          This is the kind of study that begs for further research, because the amount you can glean from it is remarkably small

          1 reply 1 retweet 19 likes
          Show this thread
        3. Health Nerd‏Verified account @GidMK 11 Jul 2019

          There are already well-known risks to maternal obesity, so adding another one - especially one as small as this - isn't going to change anyone's practice

          1 reply 0 retweets 16 likes
          Show this thread
        4. Health Nerd‏Verified account @GidMK 11 Jul 2019

          Losing weight is almost always good for your health, particularly if your BMI is over 40 This study adds almost nothing to that statement

          2 replies 0 retweets 28 likes
          Show this thread
        5. Health Nerd‏Verified account @GidMK 11 Jul 2019

          (Obvious caveat - losing weight is almost always good if your BMI is elevated)

          2 replies 0 retweets 11 likes
          Show this thread
        6. End of conversation
        1. Dianne Oickle‏ @D_Oickle 12 Jul 2019
          Replying to @GidMK

          BOOM! Nailed it

          0 replies 0 retweets 0 likes
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