Small, well controlled trial shows reversal of metabolic disease + improvements in cholesterol for group on low carb diet, even when weight kept stable. Carb restriction appears to be the key intervention.https://www.newsweek.com/low-carb-diet-reduce-risk-diseases-1444962 …
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Replying to @bigfatsurprise
Interestingly, the study was primarily on a cheese diet which was mostly due to the fact that it was funded by the dairy industrypic.twitter.com/S1LeVmRv9E
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Replying to @bigfatsurprise
Nope, but the change in carb content was apparently brought about largely with cheese and it made up a large portion of the diet according to the pre registration
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Replying to @GidMK
Interestingl how could this have changed the results, did you think?
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Replying to @bigfatsurprise
I wouldn't say it changed the results exactly, but given the context some of the design and analysis is a bit problematic - the stats, for example, look to be geared towards generating a positive finding which could have been influenced by the industry funding
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Replying to @GidMK @bigfatsurprise
Health Nerd Retweeted Health Nerd
I did a long thread over here about industry funding, it's usually not a problem for study quality per se, more an issue of direction, communication, and analysishttps://twitter.com/GidMK/status/1103539010025119744?s=19 …
Health Nerd added,
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Replying to @GidMK
Nice thread! I think there are further ways industry funding can bias trials, bc ww/o positive results that funder is unlikely to re-fund you.
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Thanks! That's true. I think that is actually what makes this study problematic, because the issues with it - no correction for multiple comparisons and switching pre registered outcomes - are things that often accompany attempts to find positive results where there aren't any
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