It's all about the weight loss, right? Additional evidence that it just ain't true! Really well done feeding study showing resolution of metabolic syndrome and atherogenic dyslipidemia with NO weight loss. https://insight.jci.org/articles/view/128308 … @Dr__Guess @bigfatsurprise
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The Big Cheese.
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While funding isn’t everything, it’s sad that this suspect funder will ultimately be dismissed. But if it was Oldways or the Grain Council all hell would break loose
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Checked http://clinicaltrials.org entry. MetS not mentioned. Prim outcome = change in PFAs + lipoproteins. These reported 3rd/4th after MetS & secondary outcomes (e.g. DEXA). Unclear allocation concealment + all unblinded. n=16, P-values only and no 95% CIs anywhere in text.
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Use of "P < 0.05" and “trend” when >0.05 suggests wide CIs close to no stat difference. No mention by authors re: size of effect. Others can comment as to whether effect sizes = meaningful. For me = exploratory findings at best. Need replicating w >n, >robust, w <COI.
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