Now, let's set aside the first 3 points that I mentioned, and just look at what blueberry supplementation did
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Here's the table of results. There was no improvement associated with blueberry supplementation in ANY OF THE MEASUREMENTSpic.twitter.com/vbxFHdeWls
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The entire basis of the article that I linked to was a small subgroup analysis of less than half the population that found some marginally significant results for one biomarker of insulin controlpic.twitter.com/VzpRNGTont
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And we can argue about the importance of this biomarker or the other, but I think it would be better to report that blueberry supplementation has no effect on: - blood sugar - insulin - blood pressure - cholesterol
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In other words, this study was entirely negative A better headline: "blueberries useless for health, study finds"
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The fact that a totally negative study is being reported as a positive result is emblematic of the power of a catchy press release, because anyone who even glanced at the table of results would realize this was total nonsense
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TBH
@nutritionorg I'm a bit surprised that the study was published as is. The discussion made much of the subgroup analysis, but barely even mentioned that there was no improvement on any of the primary or secondary outcomes in the main study itself1 reply 1 retweet 9 likesShow this thread -
I should say, the positive findings were entirely based on an analysis in statin nonusers who comprised only 50% of the study population, which also breaks randomization ping
@dnunan79@MatthewJDalby@kcklatt2 replies 0 retweets 10 likesShow this thread -
Could you elaborate on this part? Because this is where you and the researchers seem to differ
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The main place we differ is the interpretation of the results. I'd say that their findings were almost entirely negative aside from a few surrogate markers and subgroup analyses
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Reading the first paragraph of the discussion, you wouldn't know that they failed to find any improvement of blueberries on their primary outcome, or blood pressure, blood sugar, cholesterol, and insulin resistancepic.twitter.com/rglraQj7tb
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Beware evidence spin: https://blogs.bmj.com/bmj/2016/06/21/kamal-r-mahtani-beware-evidence-spin-an-important-source-of-bias-in-the-reporting-of-clinical-research/ … And outcome reporting bias: https://catalogofbias.org/biases/outcome-reporting-bias/ …
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