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what Virta are doing & their results are in line with other studies.
However, interesting to see intellectual somersaults performed to justify why the Virta COIs are not really COIs.
"Results are still results" (same true of any pharma trial?)https://twitter.com/bigfatsurprise/status/1130491276544151553 …
But the problem for me is how much of that is the program and how much may have been influenced by the study design. It's very challenging for me to interpret these results because there's no way to tell how much of a role regression to the mean might have played
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but I cannot think of a scenario in which people with type 2 diabetes of an average of 8 years duration come of their insulin as part of natural variation?
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One thing suggested by a friend of mine was the use of newer meds (SGLT2, GLP1, DPP4s). There's also decent evidence that simply being enrolled in a study can help with things like weightloss, as well as the underlying statistical variation
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