The study is here and actually it's really awesome: https://gut.bmj.com/content/early/2019/03/26/gutjnl-2018-317805 …
It doesn't have a high risk of bias. Grading can be a bit subjective, but if I were to use Cochrane's scale I'd put this at moderate-low risk of bias
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Moderate-low? My understanding was that non-blinding; A vs A+B design; cognitive aspects to treatment; and subjective self-report outcomes of this sort; are almost definitive examples of a high-risk of bias: https://handbook-5-1.cochrane.org/chapter_8/table_8_5_d_criteria_for_judging_risk_of_bias_in_the_risk_of.htm … https://handbook-5-1.cochrane.org/chapter_8/8_11_2_assessing_risk_of_bias_in_relation_to_adequate_or.htm … https://drive.google.com/file/d/1pbkUAco17D0lVziiVeUTuvaBME7dACmD/view …
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Not sure what you mean by cognitive aspects to treatment, but not necessarily. As I said, RoB assessment can be a bit subjective, but as an example it's literally impossible to blind to CBT, but within that constraint the study was very rigorous, so I'd put it as a "probably no"
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