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GidMK's profile
Health Nerd
Health Nerd
Health Nerd
Verified account
@GidMK

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Health NerdVerified account

@GidMK

Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him

Sydney, New South Wales
theguardian.com/profile/gideon…
Joined November 2015

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    1. Health Nerd‏Verified account @GidMK 6 Mar 2019

      So we know that industry funded trials are usually as good as or better than other research What does that mean for their results?

      1 reply 0 retweets 7 likes
      Show this thread
    2. Health Nerd‏Verified account @GidMK 6 Mar 2019

      To put it another way, are industry funded trials more or less likely to find positive results for the funding body?

      1 reply 1 retweet 2 likes
      Show this thread
    3. Health Nerd‏Verified account @GidMK 6 Mar 2019

      Well, we know that they're pretty good trials. If they were all fair comparisons, they should be the same or perhaps less likely

      1 reply 0 retweets 2 likes
      Show this thread
    4. Health Nerd‏Verified account @GidMK 6 Mar 2019

      But instead, when we look at the evidence, we find... Exactly the opposite Industry funded trials mostly report positive results for the funding bodypic.twitter.com/nblpNjJ564

      1 reply 0 retweets 7 likes
      Show this thread
    5. Health Nerd‏Verified account @GidMK 6 Mar 2019

      How can this be????

      1 reply 0 retweets 2 likes
      Show this thread
    6. Health Nerd‏Verified account @GidMK 6 Mar 2019

      (I'll give you a hint - the industry is definitely not always right)

      1 reply 0 retweets 2 likes
      Show this thread
    7. Health Nerd‏Verified account @GidMK 6 Mar 2019

      A few people have answered, so let's put the cards on the table That's right, it's publication bias!

      1 reply 0 retweets 6 likes
      Show this thread
    8. Health Nerd‏Verified account @GidMK 6 Mar 2019

      If we look at industry funded trials, they are almost never negative (i.e. no benefit for the funding body) It turns out that often, the negative trials just aren't published!

      4 replies 1 retweet 13 likes
      Show this thread
    9. Health Nerd‏Verified account @GidMK 6 Mar 2019

      So individual trials can be very good - meaning that industry funding isn't necessarily an issue for individual trials - but they still make a misleading picture overall

      2 replies 0 retweets 8 likes
      Show this thread
    10. Health Nerd‏Verified account @GidMK 6 Mar 2019

      If you're interested in this issue, you should follow @senseaboutsci who are doing great work getting studies registered and published

      2 replies 0 retweets 10 likes
      Show this thread
      Health Nerd‏Verified account @GidMK 6 Mar 2019

      So ultimately, saying "the industry funded this trial" doesn't necessarily mean much in terms of its quality What it does say is that you should be looking for more research overall because there may be unpublished work contradicting the findings

      10:31 PM - 6 Mar 2019
      • 2 Retweets
      • 28 Likes
      • Brett Chrest Kits Fool and 1000s of others Woo detector #ARSE, Inventor of Fire barttels Maria Nathan Boonstra, MD Epon Cherrilaf (Insert Reference Trolls Don't Get) Dr. Sean Gallagher transplantrockstar
      5 replies 2 retweets 28 likes
        1. New conversation
        2. Işıl Arıcan‏ @isil_arican 6 Mar 2019
          Replying to @GidMK

          Please unroll @ThreadReaderApp

          1 reply 0 retweets 0 likes
        3. Thread Reader App‏ @threadreaderapp 6 Mar 2019
          Replying to @isil_arican

          Hallo the unroll you asked for: Thread by @GidMK: "This is a common misconception that springs up all the time, so let's talk industry bias in scientific research Does ind […]" https://threadreaderapp.com/thread/1103539010025119744.html … Have a good day. 🤖

          0 replies 1 retweet 4 likes
        4. End of conversation
        1. New conversation
        2. CharlesLCarter‏ @CharlesLCarter3 7 Mar 2019
          Replying to @GidMK

          1/ Thanks. Excellent. I seem to recall a few comparisons in which the same drug is studied with different funding sources, results suggestive of bias. Plus as I understand it, they don’t share data. Lastly, p-hacking was only identified in 2011 and pre-trial registration

          1 reply 0 retweets 0 likes
        3. CharlesLCarter‏ @CharlesLCarter3 7 Mar 2019
          Replying to @CharlesLCarter3 @GidMK

          2/ is a recent (and often unenforced) innovation. Have these improved industry reports?

          0 replies 0 retweets 0 likes
        4. End of conversation
        1. Andrew Althouse‏ @ADAlthousePhD 7 Mar 2019
          Replying to @GidMK

          Yup. “The study was industry funded” is the laziest of trial critique. Explain why the study was poor (maybe it was! That happens) but just saying that it was industry funded isn’t a real criticism or explanation of anything.

          0 replies 0 retweets 2 likes
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        1. Douglas Michael Massing  🌈 We voted for our lives‏ @T2DRemission 7 Mar 2019
          Replying to @GidMK

          Apart from publication bias, funding sets the agenda. Whether or not funders—private or public, commercial or nonprofit—bring an agenda to the table, they determine the questions that get asked (specifically, which questions will be afforded the expense of large-scale RCTs).

          0 replies 0 retweets 0 likes
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        1. New conversation
        2. Alison Palkhivala‏ @alisonpalk 20 Mar 2019
          Replying to @GidMK

          What is your take on Marcia Angelo’s vocal and ongoing criticism of research bias? https://www.nytimes.com/2018/09/14/opinion/jose-baselga-research-disclosure-bias.html?smid=nytcore-ios-share …

          2 replies 0 retweets 0 likes
        3. Alison Palkhivala‏ @alisonpalk 20 Mar 2019
          Replying to @alisonpalk @GidMK

          *Angell. Stupid autocorrect

          0 replies 0 retweets 0 likes
        4. End of conversation

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