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GidMK's profile
Health Nerd
Health Nerd
Health Nerd
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@GidMK

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Health NerdVerified account

@GidMK

Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him

Sydney, New South Wales
theguardian.com/profile/gideon…
Joined November 2015

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    1. Health Nerd‏Verified account @GidMK 6 Mar 2019

      Health Nerd Retweeted MabelR

      This is a common misconception that springs up all the time, so let's talk industry bias in scientific research Does industry funding make a study bad - a tweetorialhttps://twitter.com/mabelyang/status/1103491457854423040 …

      Health Nerd added,

      MabelR @mabelyang
      Replying to @GidMK
      You have omitted the important fact that the studies have been funded and backed by vaccine makers. Such studies can never be objective. Statens Serum Institut & Novo Nordisk make vaccines. #ConflictOfInterest
      3 replies 13 retweets 33 likes
      Show this thread
    2. Health Nerd‏Verified account @GidMK 6 Mar 2019

      The basic idea is similar to the one in the tweet above. You can find it anywhere Industry does research. But industry wants money. Therefore, their research is hopelessly biased, because they don't do research that doesn't earn them moneypic.twitter.com/dLyoXsLDoE

      1 reply 0 retweets 6 likes
      Show this thread
    3. Health Nerd‏Verified account @GidMK 6 Mar 2019

      The thing is, this isn't just a theoretical question. We can look at industry-funded trials and compare them to non-industry funded ones

      1 reply 0 retweets 6 likes
      Show this thread
    4. Health Nerd‏Verified account @GidMK 6 Mar 2019

      There are many ways of grading studies in terms of how "good" they are. One commonly-used (and in many ways gold standard) method is @cochranecollab risk of bias tool https://methods.cochrane.org/bias/resources/rob-2-revised-cochrane-risk-bias-tool-randomized-trials …pic.twitter.com/km9rxwiqex

      1 reply 0 retweets 12 likes
      Show this thread
    5. Health Nerd‏Verified account @GidMK 6 Mar 2019

      Bias refers to elements that the study has failed to control for which may have influenced the outcome of the study For example, if the study had more dropouts in the intervention group, then it may have been biased

      1 reply 0 retweets 9 likes
      Show this thread
    6. Health Nerd‏Verified account @GidMK 6 Mar 2019

      So back to the original question Compared to non-industry trials, are industry trials (in terms of risk of bias)

      3 replies 0 retweets 4 likes
      Show this thread
    7. Gunter Kuhnle‏ @ggkuhnle 6 Mar 2019
      Replying to @GidMK

      It depends: trial sponsors (industry & non-industry) should be interested in unbiased results, and industry often has more resources to conduct them (and is more scrutinised) - so lower bias here. But that's of course not always the case.

      1 reply 0 retweets 1 like
      Health Nerd‏Verified account @GidMK 6 Mar 2019
      Replying to @ggkuhnle

      Yep the higher scrutiny is a big differential - industry trials also get better when regulators pay attention 👍

      10:27 PM - 6 Mar 2019
      • 1 Like
      • Gunter Kuhnle
      1 reply 0 retweets 1 like
        1. Gunter Kuhnle‏ @ggkuhnle 6 Mar 2019
          Replying to @GidMK

          They need to enforce GCP etc to be taken seriously - which is not the case with many other studies. Once I criticised lack of QA as reviewer of a study - editor & author agreed that it was not necessary as authors were experts in the field!

          0 replies 0 retweets 1 like
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