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GidMK's profile
Health Nerd
Health Nerd
Health Nerd
Verified account
@GidMK

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Health NerdVerified account

@GidMK

Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him

Sydney, New South Wales
theguardian.com/profile/gideon…
Joined November 2015

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    1. Kevin Bass, MS‏ @kevinnbass 9 Jan 2019
      Replying to @kevinnbass @mackinprof and

      By your standards the connection between smoking and lung cancer should be dismissed as fear mongering

      9 replies 0 retweets 8 likes
    2. Stephan J. Guyenet‏ @whsource 9 Jan 2019
      Replying to @kevinnbass @mackinprof and

      The size of an association does matter. In the GRADE method for judging/communicating the strength of a conclusion based on a body of evidence, "large magnitude of effect" is a determining factor of observational evidence strength. https://handbook-5-1.cochrane.org/chapter_12/table_12_2_c_factors_that_may_increase_the_quality_level_of_a.htm …

      2 replies 0 retweets 21 likes
    3. Sir Panda (Zad Rafi)‏ @dailyzad 9 Jan 2019
      Replying to @whsource @kevinnbass and

      If you think about it, large effects are often implausible, there are only a handful of scenarios where there have been large effects (smoking lung cancer). If anything large effects may simply be strong bias or bad estimation.

      1 reply 2 retweets 10 likes
    4. This Tweet is unavailable.
    5. Sir Panda (Zad Rafi)‏ @dailyzad 9 Jan 2019
      Replying to @dailyzad @whsource and

      Smoking and lung cancer is not a good comparison because it’s an incredibly rare outlier

      2 replies 0 retweets 4 likes
    6. Kevin Bass, MS‏ @kevinnbass 9 Jan 2019
      Replying to @dailyzad @whsource and

      Lun cancer-smoking connection came from observational evidence backed by mechanistic studies that formed the consensus. Animal protein is in the same boat.

      1 reply 0 retweets 1 like
    7. Kevin Bass, MS‏ @kevinnbass 9 Jan 2019
      Replying to @kevinnbass @dailyzad and

      You say it's impossible to establish effect with observational studies with animal protein, and consistency would demand you do the same with smoking and lung cancer.

      1 reply 0 retweets 0 likes
    8. Sir Panda (Zad Rafi)‏ @dailyzad 9 Jan 2019
      Replying to @kevinnbass @whsource and

      Kevin, the lung cancer-smoking example is never used as an example to promote the prowess of epidemiological data. Its an outlier where the increased risk was nearly 20x

      2 replies 0 retweets 1 like
    9. Health Nerd‏Verified account @GidMK 9 Jan 2019
      Replying to @dailyzad @kevinnbass and

      Now that I don't agree with. There are quite a few examples aside from smoking with similar - although not quite as high - risks. Mesothelioma/asbestos and hepatocellular carcinoma/HBV spring to mind

      2 replies 0 retweets 1 like
    10. Sir Panda (Zad Rafi)‏ @dailyzad 9 Jan 2019
      Replying to @GidMK @kevinnbass and

      good points, though smoking is like the parachute

      1 reply 0 retweets 0 likes
      Health Nerd‏Verified account @GidMK 9 Jan 2019
      Replying to @dailyzad @kevinnbass and

      Yeh it's definitely an outlier, but that's not necessarily because of effect size it's more to do with how limited the exposure is. I can't think of another disease state that has such a simple and easily-identifiable risk

      4:47 PM - 9 Jan 2019
      • 1 Like
      • Kevin Bass, MS
      0 replies 0 retweets 1 like

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