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GidMK's profile
Health Nerd
Health Nerd
Health Nerd
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@GidMK

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Health NerdVerified account

@GidMK

Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him

Sydney, New South Wales
theguardian.com/profile/gideon…
Joined November 2015

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    1. Dr David Robert Grimes‏Verified account @drg1985 17 Dec 2018

      ..this is somewhat murkier. Firstly, the mechanism of action (if it exists) isn't clear. Perhaps asbestos could travel through vagina, causing chronic inflammation of the ovaries. But there's little evidence for this. What about the epidemilogical data? (6/n)pic.twitter.com/QsajqvvVrj

      1 reply 0 retweets 3 likes
      Show this thread
    2. Dr David Robert Grimes‏Verified account @drg1985 17 Dec 2018

      ..the 'strongest' evidence comes from case control studies. While there are conflicting findings, a 2015 study suggested women who report using talc in the genital region are more likely to develop ovarian cancer (7/n) https://journals.lww.com/epidem/Fulltext/2016/05000/The_Association_Between_Talc_Use_and_Ovarian.6.aspx …pic.twitter.com/j8nbxTXqTG

      1 reply 0 retweets 6 likes
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    3. Dr David Robert Grimes‏Verified account @drg1985 17 Dec 2018

      But this evidence is actually weaker than you'd think - for one thing, as I've ranted on before, that's relative risk. Heavy talc users would see life-time risk of about 1.7%, whereas non-users would have a 1.3% lifetime risk of the cancer. (8/n)pic.twitter.com/mOnlPaapf2

      2 replies 1 retweet 21 likes
      Show this thread
    4. Dr David Robert Grimes‏Verified account @drg1985 17 Dec 2018

      Even inside those groupings (talc users versus non-talk users) there were many other factors that mattered; whether the women were on hormonal replacement therapy, whether they were over-weight, many other known risk factors for cancers. But there's a bigger problem.. (9/n)pic.twitter.com/yOrNYagbj1

      1 reply 0 retweets 6 likes
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    5. Dr David Robert Grimes‏Verified account @drg1985 17 Dec 2018

      The huge issue is that these were case-control studies. Essentially, self reported data. This is the weakest possible evidence, because human recall is pretty bloody flawed. With better study design, the talc-cancer link seems to disappear (10/n) https://www.scientificamerican.com/article/evidence-on-talc-cancer-risk-differs-for-jurors-researchers/ …pic.twitter.com/oGJZenLSo8

      2 replies 1 retweet 14 likes
      Show this thread
    6. Dr David Robert Grimes‏Verified account @drg1985 17 Dec 2018

      For this reason, most cancer organisations do not believe that talc to the genitals is particularly risky. Here's the American cancer society on it, for example: (11/n) https://www.cancer.org/cancer/cancer-causes/talcum-powder-and-cancer.html …pic.twitter.com/2P4lEgd3Gb

      1 reply 2 retweets 10 likes
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    7. Dr David Robert Grimes‏Verified account @drg1985 17 Dec 2018

      Should people be worried? I wouldn't be. If there is risk it's miniscule in comparison to known risks. Also, like all risks, dose matters - precisely how much talc are you going to use?! If you are worried, no harm is decreasing your exposure, but also likely no need (12/n)pic.twitter.com/8jtmaGKgJ4

      1 reply 0 retweets 17 likes
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    8. Dr David Robert Grimes‏Verified account @drg1985 17 Dec 2018

      Also, correlation is not causation - this cannot be repeated enough. Ice cream sales are correlated with drowning, but they don't cause it! Their appparent relationship is consequence of a lurking variable - good weather. Basic lab science required to prove X causes Y! (13/n)pic.twitter.com/51NHKUpR4r

      3 replies 2 retweets 29 likes
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    9. Dr David Robert Grimes‏Verified account @drg1985 17 Dec 2018

      Dr David Robert Grimes Retweeted Dr David Robert Grimes

      Finally, you might ask why juries award such massive pay outs when the evidence base is so weak? I'd suggest standards evidence on court << scientific evidence. I direct you to my previous musings on the subject (14/14)https://twitter.com/drg1985/status/1028239030515916800 …

      Dr David Robert Grimes added,

      Dr David Robert GrimesVerified account @drg1985
      In the last year, courts have ruled that 1) Round-up causes cancer 2) Talc causes cancer 3) Wi-Fi causes cancer 4) Vaccines cause SIDs All of which are completely bloody wrong, clashing entirely with scientific data. The law is an ass - especially when it comes to science.
      Show this thread
      2 replies 3 retweets 26 likes
      Show this thread
    10. Dr David Robert Grimes‏Verified account @drg1985 17 Dec 2018

      ...thread might be of interest to @DrRobertOConnor @gorskon @GidMK @DrJenGunter @TheSciBabe @AliceEmmaLouise @_captainscience & usual suspects!

      2 replies 2 retweets 18 likes
      Show this thread
      Health Nerd‏Verified account @GidMK 17 Dec 2018
      Replying to @drg1985 @DrRobertOConnor and

      Interesting! Honestly I bought into the hype, nice to see some clarity here

      11:26 AM - 17 Dec 2018
      • 3 Likes
      • Amanush Dr Robert O'Connor Captain Science PhD
      0 replies 0 retweets 3 likes

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