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GidMK's profile
Health Nerd
Health Nerd
Health Nerd
Verified account
@GidMK

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Health NerdVerified account

@GidMK

Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him

Sydney, New South Wales
theguardian.com/profile/gideon…
Joined November 2015

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    1. Health Nerd‏Verified account @GidMK 16 Dec 2018
      Replying to @PeterFaberSP @drjasonfung

      Well, either weight gain is all about insulin or it isn't. If it is, it should be in every situation-even starvation Otherwise, it's more complex than you want it to be

      1 reply 0 retweets 0 likes
    2. Peter Faber‏ @PeterFaberSP 16 Dec 2018
      Replying to @GidMK @drjasonfung

      https://lowcarbhighfatketo.com/the-only-3-ways-to-keep-insulin-low/ …

      1 reply 0 retweets 0 likes
    3. Health Nerd‏Verified account @GidMK 16 Dec 2018
      Replying to @PeterFaberSP @drjasonfung

      But we're not talking about keeping insulin low. We're talking about eating nothing at all and taking large amounts of insulin. If calories have nothing to do with weight gain, presumably you wouldn't lose weight

      1 reply 0 retweets 0 likes
    4. Peter Faber‏ @PeterFaberSP 16 Dec 2018
      Replying to @GidMK @drjasonfung

      You are talking about that, and I'm tired of this. Muted.

      1 reply 0 retweets 0 likes
    5. Health Nerd‏Verified account @GidMK 16 Dec 2018
      Replying to @PeterFaberSP @drjasonfung

      I'm still waiting for an answer. Seems a fairly easy thing to explain, if your model is correct

      1 reply 0 retweets 0 likes
    6. Jim Johnson, Ph.D.‏ @JimJohnsonSci 16 Dec 2018
      Replying to @GidMK @PeterFaberSP @drjasonfung

      Insulin is not a nutrient. It directs nutrients into storage. That’s the model. I hope that answers your question.

      1 reply 0 retweets 0 likes
    7. Health Nerd‏Verified account @GidMK 16 Dec 2018
      Replying to @JimJohnsonSci @PeterFaberSP @drjasonfung

      Yes I guess it does. That would seem to invalidate the basic argument that insulin = weight gain by definition, as hyperinsulinaemia is a necessary but not sufficient precondition for weight gain

      1 reply 0 retweets 1 like
    8. Jim Johnson, Ph.D.‏ @JimJohnsonSci 16 Dec 2018
      Replying to @GidMK @PeterFaberSP @drjasonfung

      I don’t think anyone has argued that insulin can contribute to weight gain in the absence of nutrients. However, from a biological standpoint, hyperinsulinemia meets the definitions of being necessary (our work; others) and sufficient (insulin clinical) in standard contexts.

      1 reply 0 retweets 0 likes
    9. Health Nerd‏Verified account @GidMK 16 Dec 2018
      Replying to @JimJohnsonSci @PeterFaberSP @drjasonfung

      Hmmmm but surely the hypothesis should hold in all situations? Otherwise presumably by definition it is more complex than hyperinsulinaemia causing weight gain

      1 reply 0 retweets 1 like
    10. Jim Johnson, Ph.D.‏ @JimJohnsonSci 16 Dec 2018
      Replying to @GidMK @PeterFaberSP @drjasonfung

      The hypothesis that is tested is a multipart framework. Diet/lifestyle acting via hyperinsulinemia promotes fat deposition, insulin resistance and eventually type 2 diabetes. You can’t just drop the first part or you are left with a strawman.

      1 reply 0 retweets 0 likes
      Health Nerd‏Verified account @GidMK 16 Dec 2018
      Replying to @JimJohnsonSci @PeterFaberSP @drjasonfung

      Mmmm but then how do you separate the diet/lifestyle out from the hyperinsulinaemia? Seems like a chicken/egg problem is built in

      10:58 PM - 16 Dec 2018
      • 1 Like
      • Pissed Off PT
      1 reply 0 retweets 1 like
        1. Jim Johnson, Ph.D.‏ @JimJohnsonSci 16 Dec 2018
          Replying to @GidMK @PeterFaberSP @drjasonfung

          There are some feedback loops but we can and have separated them. It’s easiest to do in the lab. We’ve written a few papers on this, but basically you keep diet the same and reduce insulin production directly. You can watch the webinar in my pinned tweet.

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