I need some #epitwitter help with this article (https://www.ncbi.nlm.nih.gov/pubmed/29995914 ). Crude rate of secondary outcome (coronary PCI) in marijuana users was 35% vs 32% in controls. Multivariable OR is 0.73 (0.67±0.80), indicating reduced odds of PCI in marijuana users. What am I missing?
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Thanks for the insight! Much appreciated.
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Haven’t had a chance to read the linked article but yes. It is possible for the direction of an “unadjusted” relationship to reverse in direction after adjustment for a confounder.
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