Hoping for a @virtahealth 2.0 with randomization and some more guidance on emphasizing unsaturated fats. My bets are on much better lipid profile than they saw with just the large weight loss.https://twitter.com/YoniFreedhoff/status/1065199280409989121 …
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Replying to @KCKlatt @virtahealth
Yes but they've got funding now why would they spend millions just to actually see if the product works?
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Do you think Virta came up with their product out of thin air? A random stroke of luck? Do you think their published results demonstrating efficacy are fabricated or have no meaning?
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No, I was being glib about the fact that they appeared to have had very significant funding and yet ran a study that had several fairly major weaknesses (I.e. unrandomized) when it would've been just as easy to do it right
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Ah! Glib gets me every time. Clearly they achieved results needed to excite investors but didn't create a study that was going to create a complete paradigm shift in standard of care/guidelines, although suspect they have definitely 'moved the needle.'
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I don't think they have, at least where I work. Everyone looked at it and said it was a marketing stunt or something similar. People were much more impressed with DIREcT
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I can see how researchers are excited by DiRECT based on trial design where as physicians working with patients are excited by virta’s results.
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Actually, not so much. None of the clinicians I know has so far been impressed with Virta, particularly after seeing the ~$6,000 AUD per year price tag
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If finance is concern then you need to run the numbers. What is the cost savings of insulin reduction/elimination, other medications, and then estimate decrease in T2d complications based on lowering a1c, ldl-p, bp, crp, etc. etc Suspect $6000 is very cost effective.
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But we have no way of knowing if it's cost-effective. For that, we'd have to have an RCT comparing Virta to at least normal care (or ideally best-practice care), and create an incremental cost-effectiveness ratio. That's kind of the problem with running a flawed trial!
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And it's a really important question. You can run a weekly clinic that sees thousands each year for the same price as the subscription fee for 60-odd patients on Virta
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The cost would be dramatically less with our mom and pop shoppe model.
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