"Effects of low-carbohydrate- compared with low-fat-diet interventions on metabolic control in people with type 2 diabetes: a systematic review including GRADE assessments" https://academic.oup.com/ajcn/article-abstract/108/2/300/5051863 …
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Replying to @JimChinnis @whsource
Hilariously, they didn't consider differences in medication use required to reach those HbA1c levels. This failure to combine all glycemic outcomes is why meta-analysis of T2DM diet studies is worthless.
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That would perhaps apply to studies that were not randomized, but is not a genuine critique of this analysis
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Please explain how you would combine both HbA1c reduction and medication reduction into a common outcome for meta-analysis. These are two separate markers of glycemic control which are usually traded off within RCTs. An individual RCT can give this data clearly.
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You wouldn't? That would be two outcomes. RCTs don't combine them either. But they do randomize, thus applying any effects equally across both groups
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But it increases noise.
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How so?
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I'd dig deeper, but article is hidden behind a paywall.
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I had given up on Sci-Hub! Now I have to find time to read the paper! I suspect my comment may apply to the RCTs but not really the meta-analysis, which has to work with what's out there.
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