It is always fun to write a lengthy blog, a detailed thread, and have someone strawman two minor points in that broad discussion to argue that you're wronghttps://twitter.com/sib313/status/1032217398118637576 …
...that alcohol is providing a benefit, and there are known, direct causal pathways between alcohol and harm, it is reasonable to conclude that even moderate intakes of alcohol are harmful. This has also been shown in a number of epidemiological studies...
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...such as this one, from NZ, where the association appeared significantly protective but was entirely mitigated through controlling for social confounders: https://academic.oup.com/psychsocgerontology/article-abstract/doi/10.1093/geronb/gbw152/2645642/The-Health-Benefits-of-Moderate-Drinking-in-Older?redirectedFrom=fulltext …
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I am not denying the evidence, merely pointing out that there is good reason to believe that the common interpretation - moderate drinking is beneficial - runs counter to a significant body of evidence as well as biological plausibility
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Again this argument cuts both ways. I could mention the plausible biological pathways that contribute to cardiovascular benefits for small levels of alcohol consumption.
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Potentially plausible biological mechanisms, largely based on rodent and in vitro studies, are in no way as convincing as the enormous body of clinical evidence on the harms of alcohol
End of conversation
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