On flawed @TheLancet study alleging low-carb shortens life: 1. low-carb group was (hopelessly) confounded by higher rates of smoking, diabetes, obesity 2. study contradicted by 70+ trials--far more rigorous data--all of which show improved health on low carb 1/2
Here is the study, I'd recommend the "methods" section it's very enlightening https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(18)30135-X/fulltext#seccestitle80 …
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I read it on the tube. I burst out laughing. Literally.
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It is very well-written, most scientific research is rather dry

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It's crucial not to adjust for mediators or their proxies, as explained by
@yudapearl below. If carbohydrates cause CVD via a mediator, e.g. excess insulin production, then diabetes, and arguably energy intake, are proxies, so adjusting for them renders the analysis impotent. 1/pic.twitter.com/B4A0ketuF4
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It's also odd that they based the carbohydrate levels solely on baseline and visit 3. What was with with all the other data?
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