Genes & Development

@GenesDev

Genes & Development publishes high-quality scientific research papers in the areas of molecular biology, cancer biology, development, and related fields.

New York, USA
genesdev.org
Vrijeme pridruživanja: srpanj 2009.
234 fotografije ili videozapisa Fotografije i videozapisi

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  1. Prikvačeni tweet
    2. sij

    January issue of is now online!

    2 proslijeđena tweeta 8 korisnika označava da im se sviđa
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  2. 16. sij

    In this study Zhang et al. demonstrate that Snf2h, the catalytic subunit of ISWI family complexes, is critical in driving meiotic progression.

    2 proslijeđena tweeta 4 korisnika označavaju da im se sviđa
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  3. 16. sij

    In this study Denholtz et al., propose a model in which the microbe-induced transcriptional signature of activated neutrophils is driven by activated enhancer repertoires.

    1 proslijeđeni tweet 1 korisnik označava da mu se sviđa
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  4. 16. sij

    In this study Singh et al., show that Hap2-Ino80 destabilises H3 nucleosomes on centromere DNA through transcription-coupled histone H3 turnover, driving the replacement of resident H3 nucleosomes with CENP-A nucleosomes.

    4 proslijeđena tweeta 3 korisnika označavaju da im se sviđa
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  5. 15. sij

    In this study Chen et al. elucidate the mechanism by which meiotic cells modulate their kinetochore composition through regulated Aurora B-dependent Ndc80 degradation.

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  6. 15. sij

    In this study Slaidina et al., use single cell RNA sequencing to identify transcription signatures for each cell type in the developing Drosophila gonad.

    4 proslijeđena tweeta 2 korisnika označavaju da im se sviđa
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  7. 13. sij

    Here the authors show that Ringer acts as a hub for microtubule regulators that relays cellular status information, in order to instruct neuroregeneration.

    2 proslijeđena tweeta 2 korisnika označavaju da im se sviđa
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  8. 2. sij

    This Outlook discusses Cho et al.’s finding in this issue of Genes & Dev showing that CDK7 directly phosphorylates YAP/TAZ/Yki in the nucleus, in a manner independent of the Hippo cascade and from CDK7 basal transcriptional effects.

    2 proslijeđena tweeta 5 korisnika označava da im se sviđa
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  9. 2. sij

    This Outlook discusses Shyian et al.’s finding in this issue of Genes & Dev showing that topoisomerases play an unexpected role in the regulation of programmed fork pausing in S. cerevisiae.

    1 proslijeđeni tweet 3 korisnika označavaju da im se sviđa
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  10. 2. sij

    Here the authors revisit the current models explaining imprinting regulation in plants, and discuss novel regulatory mechanisms that function independently of parental DNA methylation asymmetries.

    10 proslijeđenih tweetova 31 korisnik označava da mu se sviđa
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  11. 2. sij

    Here the authors summarize the current understanding of the role of 53BP1 in DSB repair at deprotected telomeres, in class switch recombination in the immune system, and in the context of PARPi-treated BRCA1-deficient cells.

    9 proslijeđenih tweetova 27 korisnika označava da im se sviđa
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  12. 30. pro 2019.

    Here the authors demonstrate that TRPS1 can function as a context-dependent tumor suppressor in breast cancer, while being essential for growth and differentiation of normal mammary epithelial cells.

    1 reply 3 proslijeđena tweeta 6 korisnika označava da im se sviđa
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  13. 30. pro 2019.

    This study identifies an unanticipated layer of Hippo pathway regulation, defines a novel mechanism by which CDK7 regulates tissue growth, and implies CDK7 as a drug target for Yap/Taz-driven cancer.

    3 proslijeđena tweeta 7 korisnika označava da im se sviđa
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  14. 30. pro 2019.

    Here the authors reveal a conserved mechanism for 5′ tRNA fragment control of noncoding RNA biogenesis and, consequently, global chromatin organization.

    19 proslijeđenih tweetova 36 korisnika označava da im se sviđa
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  15. 30. pro 2019.

    Here the authors reveal a feed-forward interplay between immediate early transcription of AP-1 and Hippo pathway function.

    1 proslijeđeni tweet 1 korisnik označava da mu se sviđa
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  16. 30. pro 2019.

    Here the authors identify Decapentaplegic (Dpp) as a myokine that can signal from the muscle to the brain to control feeding by altering Dopamine synthesis through transcriptional regulation of tyrosine hydroxylase.

    2 proslijeđena tweeta 6 korisnika označava da im se sviđa
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  17. 30. pro 2019.

    Here the authors show that forks pause at proteinaceous RFBs through a ‘sTOP’ mechanism (‘slowing down with TOPoisomerases I-II’), which contributes to protecting cells from topoisomerase-blocking agents.

    6 proslijeđenih tweetova 19 korisnika označava da im se sviđa
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  18. 11. pro 2019.

    Exploring the Building Blocks of Life: Allosteric Vs Torpedo Model

    2 proslijeđena tweeta 1 korisnik označava da mu se sviđa
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  19. 11. pro 2019.

    Pioneering research gives fresh insight into one of the pivotal building blocks of life.

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  20. 9. pro 2019.

    Here the authors propose that forks pause at proteinaceous RFBs through a “sTOP” mechanism (“slowing down with topoisomerases I–II”), which contributes to protecting cells from topoisomerase-blocking agents.

    1 proslijeđeni tweet 7 korisnika označava da im se sviđa
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