Gautier Richard

@Gautier_Rich4rd

PhD, Computational biologist INRAE. Exbioinfo w/ Fascinated by vinyls & music

Rennes, France
Vrijeme pridruživanja: lipanj 2019.

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  1. Prikvačeni tweet
    14. lis 2019.

    Read the new Lab paper: guided reveal conserved regulatory on and autosomes despite extensive shuffling in . ⬇️Description in the comments below⬇️

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  2. articles introduced by . I hope this will become the norm in the next 10 years. This would improve papers SO MUCH and help meeting requirements.

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  3. 1. velj

    As outlined in his tweet there's also to parse HOMER motifs output. Really handy. I quitted using HOMER a while ago notably because of the pain of parsing the outputs.

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  4. 1. velj

    "marge" a R interface for "HOMER". Identify those motifs you like dearly and parse them easily within R with your favorite motif caller. REALLY nice!

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  5. proslijedio/la je Tweet
    1. velj

    retraite à 65 ans ancien système : 3089 euros net/mois retraite à 65 ans nouveau système : 2553 euros net/mois un grand merci à pour le partage des ses données et réflexions 2/2

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  6. proslijedio/la je Tweet
    1. velj
    Odgovor korisnicima

    Our bioinformatics guy said the same in this debunking of the paper:

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  7. proslijedio/la je Tweet
    30. sij
    Odgovor korisniku/ci

    And yet targeted methylation and demethylation assays can have sustained impacts on transcription level. Causality can be in both directions.

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  8. proslijedio/la je Tweet
    30. sij

    First the chromatin opens, then the DNA methylation is lost. The chromatin opens because transcription factors (TFs) target those loci. TFs tell DNA methylation and nucleosomes what to do at cis-regulatory loci. Not the other way around. Your textbook needs a rewrite.

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  9. proslijedio/la je Tweet
    31. sij

    Il y a 20 ans, la recherche sur les était un 'sous-domaine' peu financé de la virologie. La recherche fondamentale est "inutile" jusqu'à ce qu'elle devienne soudainement la chose la plus importante au monde. Imaginez si elle n'était plus du tout financée.....

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  10. 31. sij

    The main trick I learned from those slides

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  11. 31. sij
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  12. proslijedio/la je Tweet
    30. sij

    New Marchantia genome reassembly starring H3K27me3! Thanks to everyone who helped bring this together! Website with chromatin profiles, updated gene names:

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  13. 30. sij

    Hi people. I was doing comparative the other day and was day dreaming: will HiGlass support vs genome alignment matrices and their respective annotation plotting? One genome on the X, another one on the Y and the rearrangements in the central panel?

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  14. 30. sij

    HiGlass in Jupyter Notebooks 😃! It's a great tool to visualize any genomic data interactively, but the main focus is on Hi-C matrices exploration.

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  15. proslijedio/la je Tweet
    29. sij

    is basically the Christmas morning of finding out about new packages. 🎁

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  16. proslijedio/la je Tweet
    23. sij

    I’m thrilled to announce the publication of the quantitive proteomic profiling of the Cancer Cell Line Encyclopedia. The in collaboration with colleagues at Novartis and the Broad we measured the proteomes of 375 cell lines from various tumor lineages (1/13)

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  17. 29. sij

    I was discussing this with my brother who is a person. The community is awesome and is pushing people to not constantly reinvent the wheel! Also, what a pleasure to stumble upon a package that does more than what you were dreaming about. {UpSetR} comes to mind.

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  18. proslijedio/la je Tweet
    29. sij

    The Pacific Ocean is so acidic that it's dissolving Dungeness crabs' shells

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  19. proslijedio/la je Tweet
    28. sij

    Examination of DNA methylation across arthropods from . Some interesting findings: 1) more nuanced view of DNMT and ALK enzyme co-evolution 2)conservation of nucleosome positioning and DNAme 3) Body methylation = still confusing. 🐞🦗🕷️🦂🐜

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  20. proslijedio/la je Tweet
    29. sij

    Pleased to announce that v2.0 (SLABS FOR DAYS edition) hit CRAN today. Lots of new stuff in this version: A THREAD

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  21. proslijedio/la je Tweet
    28. sij
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