Gian M. Franceschini

@GMFranceschini

Comp bio, interested in cancer (epi)genomics and machine learning, PhD candidate at , Me = f( 🔬🧬💻 💿🎛️💿🏃‍♂️ 🖋️🕉️🕯️🌌☄️🐺🤖 )

Trento, Italy
Vrijeme pridruživanja: svibanj 2014.

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  1. proslijedio/la je Tweet
    prije 5 sati

    From reads to insight: a hitchhiker’s guide to ATAC-seq data analysis

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  2. proslijedio/la je Tweet
    prije 10 sati

    Asked to write a chapter about RNA-seq counts modeling, I used bookdown to put all the material online. Includes some new workflow pieces like tximeta for import and swish for transcript level:

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  3. proslijedio/la je Tweet
    2. velj

    2015 paper showing how a Chinese bat recombined with a SARS-CoV can use ACE2 to efficiently enter human airway cells and replicate, suggesting “a potential risk of SARS-CoV re-emergence from viruses currently circulating in bat populations.”

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  4. 31. sij

    When unpredictable circumstances turn for good: waiting for her laptop to come, the Italian senator and scientist Elena Cattaneo gives an inspiring speech about gratitude, political commitment and the fight for the truth.

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  5. proslijedio/la je Tweet
    30. sij
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  6. proslijedio/la je Tweet
    30. sij

    First the chromatin opens, then the DNA methylation is lost. The chromatin opens because transcription factors (TFs) target those loci. TFs tell DNA methylation and nucleosomes what to do at cis-regulatory loci. Not the other way around. Your textbook needs a rewrite.

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  7. proslijedio/la je Tweet
    30. sij

    is offering a sabbatical program for scientists (PIs, Postdocs, staff scientists) working on theory-based research (statistics, modelling, theoretical concepts). If interested have a look here:

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  8. proslijedio/la je Tweet
    29. sij

    Congrats to Claudio and Marica for the creation of the first human organoid-based model of Group3 Medulloblastoma.

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  9. proslijedio/la je Tweet
    28. sij

    Me explaining the execution order of my Jupyter notebook cells.

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  10. proslijedio/la je Tweet
    28. sij

    Very nicely written and illustrated. The future of controllable gene expression is bright.

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  11. proslijedio/la je Tweet
    28. sij

    Everyone is making major breakthroughs in AI while my neural network just learned how to be a line

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  12. proslijedio/la je Tweet

    Don't assume good health is forever. Don't assume a sharp mind is forever. Don't assume your loved ones are forever. Don't assume you have unlimited time. Do the things you want to do while you have the opportunity, and hug your loved ones close.

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  13. proslijedio/la je Tweet
    25. sij

    Following a few requests, here’s the (now-required) Twitter summary of our paper on 'transcriptional scanning' in the testes.

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  14. proslijedio/la je Tweet
    25. sij

    I am very curious how the pre-print haters feel about now that it is playing a staring role in understanding the coronavirus outbreak

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  15. 23. sij
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  16. 23. sij

    Impressive and exciting work: powerful insights from scRNAseq + publicly available data uncover novel mutational and repair mechanisms. A really fulfilling read.

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  17. proslijedio/la je Tweet
    22. sij
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  18. proslijedio/la je Tweet

    Frequently mutated regulatory elements in cancer

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  19. proslijedio/la je Tweet
    20. sij

    5.10.0 is released. It introduces integration, bringing the best of two worlds together: Scalable, modular, and readable data analysis definition with and fast interactive prototyping of individual steps (e.g. for plotting) with Jupyter. 1/n

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  20. proslijedio/la je Tweet
    19. sij

    Ok so in this game for some reason you gotta be first for a while and then you gotta be last to win

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