Antifungal Stewardship in Solid Organ Transplantation presented by @JGPharmD at #ACCPAM19pic.twitter.com/XouVr1Y3Sx
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.@jgpharmd: "antifungal resistance is likely underappreciated since many institution do not routinely test Candida species susceptibilities" #accpam19
C. auris concerning due to multi-drug resistance + it is extremely hard to eradicate.pic.twitter.com/zZxZrkGo2Y
so how do fungi become resistant? most common resistance of Candida spp. to echinocandins is mutations in fks genes which change glucan synthetase so the drugs are ineffective. #accpam19pic.twitter.com/7nXuCFlzaw
CLSI breakpoints only exist for Candida spp., EUCAST has Aspergillus breakpoints. #ACCPAM19pic.twitter.com/AOKfQh54Bn
opportunities for antifungal stewie: RDT with stewie team intervention, early suspicion/detection of fungal infections, and discontinuing empiric therapy if it is no longer necessary #accpam19 @JGPharmD points out how invasive fungal disease is both overtreated and underdiagnosedpic.twitter.com/EaATcryypt
.@JGPharmD shows importance of early initiation of antifungal therapy in patients with candidemia, published by @GareyKgarey and colleagues #accpam19
https://www.ncbi.nlm.nih.gov/pubmed/16758414 pic.twitter.com/ibxCLE3xHx
old and new developments in antifungal rapid diagnostics (table created by @JGPharmD) #ACCPAM19pic.twitter.com/055g2wRy45
.@jgpharmd: "the stewardship implication is clear- you should start therapy for candidemia with an echinocandin" #accpam19 https://www.ncbi.nlm.nih.gov/pubmed/17568028
https://www.ncbi.nlm.nih.gov/pubmed/30289478 pic.twitter.com/nKK7N3YkMJ
infectious diseases consultation improves candidemia outcomes #accpam19pic.twitter.com/XtaGgHugtQ
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