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Eric Topol

@EricTopol

The BQ.1.x wave projection for the US, and calculations for many other countries based on growth advantage vs BA.5, by

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BQ.1.1 and XBB.1 continue their international spread. While it's still early days, BQ.1.1 appears to be the faster one in a range of countries (Australia, Belgium, Denmark & USA have seen enough cases for a head to head comparison). More details at github.com/gerstung-lab/S

3:31 PM · Oct 22, 2022

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Eric, Do we have any pre-releases discussing BQ.1.x neutralization testing with serum from BA.4/5 vaccinated individuals?

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Best I've seen is from

@yunlong_cao

and colleagues

biorxiv.org

Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution

Continuous evolution of Omicron has led to numerous subvariants that exhibit growth advantage over BA.5. Such rapid and simultaneous emergence of variants with enormous advantages is unprecedented....

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Sure but in NY BQ.1x will be predominant in 2 weeks, based on rise from 6%>11%>20% in 3 weeks. The proof will soon be in the pooh-ding, as a trend, and per hosp:ICU & hosp:death ratios, now that CDC doesn't report daily cases & deaths. Expect Paxlovid&test kit shortages in '23?

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Somewhat can't ignore recent rises in deaths matching recent hospitalization spikes in EU... and that current deaths are worse than 1 year ago, despite availability of Bivalent booster & Paxlovid for most vulnerable. Waning efficacy VS variant evasiveness VS reinfection risks?

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never listen to someone von scheiss germany

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Those obscure names like BQ.1.x are hard to remember. We should give the variants names like we do for hurricanes. The scientists can use the obscure names. I want to hear: Variant Bob Variant Cathy Variant Dave Etc.

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🎼I’m dreaming of a BQ.1.x Christmas🎵

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