What to make of Omicron's BA.1 and (sister) BA.2 lineages?
Both are hyper-mutated with over 50 mutations but many are different, particularly in the spike and ORF1a regions outbreak.info /1
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There's not any functional or epidemiological data to show any meaningful differences....yet. But BA.2 has become dominant in Denmark, out-competing BA.1, and its prevalence is rising in India, Singapore, Sweden, the UK and other countries /2 Graph via
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The spread of BA.2 supports increased transmissibility (hard to imagine beyond BA.1, O's sister). On Jan 21st, UK designated it as a variant under investigation ft.com/content/34fef1 More to learn, keep 👀, no reason for distress at this point (we already have enough of that)
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Can one become sick with both variants at different times?
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My biggest question with BA.2 (and BA.1) is around reinfection after regular old omicron...
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