We've tried to advocate with no success to date
https://www.scientificamerican.com/article/to-beat-covid-we-may-need-a-good-shot-in-the-nose/ … @sciam w/ @danieloran @scrippsresearch @ScrippsRTI
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I still cannot understand why intranasal vaccines have not been given top priority, given their remarkable allure to block Covid transmission; an excellent explainer for why and status @ScienceMagazine https://science.sciencemag.org/content/373/6553/397 …
w/@ScienceVisualspic.twitter.com/6VHG90kbc8
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The case for a mucosal (intranasal) vaccine for
#SARSCoV2 made very well here, along with the unmet need for many other pathogens https://www.nature.com/articles/s41577-021-00583-2?utm_source=dlvr.it&utm_medium=twitter … New review@NatRevImmunol via, H/T@RTKasepic.twitter.com/lssILkjxc9
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Is this why people are hesitant? sounded like from the survey y'all referenced, is this true?
Kiitos. Käytämme tätä aikajanasi parantamiseen. KumoaKumoa
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None of them are mRNA-type. Cannot be as effective as mRNA ones, right?
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On the contrary, intranasal vaccines would potentially be more efficacious even against asymptomatic infection as it would provide localized immunity in the URT where SARS-CoV-2 would otherwise latch on to. An example of a greay intranasal vaccine is Flumist for influenza.
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Bharat Biotech Intranasal Vaccine is in Phase 3 Human trials. It is developed with the support of a university in Washington.
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China is also working on one. http://www.xinhuanet.com/english/2021-06/11/c_1310003298.htm …
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Great timing. There was an article on intranasal vaccines by Dr.
@KatherineJWu almost a year ago to the date. With comments by Dr.@VirusesImmunity, who has consistently advocated on the importance of the mucosal route of vaccination.https://www.nytimes.com/2020/07/14/health/coronavirus-nasal-vaccines.html … -
I'm guessing you saw this, but FYI the Altimmune one failed a few weeks ago. Probably has more to do with the Ad5 vector than the delivery though.https://endpts.com/altimmune-abandons-ship-on-intranasal-covid-19-vaccine-refocusing-on-liver-obesity-programs-after-trial-flop/ …
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