Je kan informatie over je locatie aan je Tweets toevoegen, bijvoorbeeld je stad of exacte locatie, via het web en applicaties van derden. Je kan altijd de locatiegeschiedenis van je Tweets verwijderen. Meer informatie
Today's "breakthrough" announcement is unlikely to be any breakthrough. 1. Convalescent plasma has no randomized trials. It contains many antibodies that have no neutralizing effect. If it has efficacy, it will be be relatively modest, at best.
2. There are no new, large-scale randomized trials that have been completed with repurposed drugs; the combination of JAK inhibitor (Baricitinib) and Remdesivir may have results but it only has 400 patients and no replicationhttps://investor.lilly.com/news-releases/news-release-details/lilly-begins-phase-3-clinical-trial-baricitinib-hospitalized …
3. Type 1 interferon (intranasal) early, preventive therapy has considerable promise (reviewed w/ @VirusesImmunity and this
; there are many trials but they are in progress
https://twitter.com/EricTopol/status/1293755617807462400 …
https://twitter.com/EricTopol/status/1296935589728538624 …pic.twitter.com/YMPXf3PXXs
4. True breakthroughs in medicine are exceedingly rare.
It is even more rare—actually unprecedented—for they to be announced by a politician, no less a @POTUS
In the context of other magic and cures that have similarly been proclaimed in recent months, this all aligns well.
5. It's even worse than this. There is no breakthrough and the @US_FDA commissioner @SteveFDA has caved to Trump's pressure (including yesterday's tweet) to promote it as if there was one.
@statnews @NicholasFlorko
https://www.statnews.com/2020/08/23/fda-under-pressure-from-trump-expected-to-authorize-blood-plasma-as-covid-19-treatment/?utm_content=buffer405b9&utm_medium=social&utm_source=twitter&utm_campaign=twitter_organic …pic.twitter.com/r3BlcCOJGf
Outrageous to listen to @realDonaldTrump @secAzar @SteveFDA claiming a 35% improved survival in an observational preprint study compared w/ late-treated patients. There's no evidence to support any survival benefit. 2 days ago FDA's website stated there was no evidence for an EUA
Here's the 8/12 preprint the claim is based on https://www.medrxiv.org/content/10.1101/2020.08.12.20169359v1.full.pdf … These were 2 exploratory analyses without control patients, with multiple confounders, eg early v late Rx The improvement of survival with a high antibody level was a post-hoc determination from stored samplespic.twitter.com/r9Aj2YUCrf
The new FDA website headline "Another Achievement in Administration's Fight Against Pandemic" https://www.fda.gov/news-events/press-announcements/fda-issues-emergency-use-authorization-convalescent-plasma-potential-promising-covid-19-treatment … (I have never seen such a statement with any FDA approval)pic.twitter.com/f3za14kSGH
But what about the MyPillow guy’s homeopathic tincture? 
needs zinc
All about the Trump show. No real science.
Twitter is mogelijk overbelast of ondervindt een tijdelijke onderbreking. Probeer het opnieuw of bekijk de Twitter-status voor meer informatie.
